Evidence map›Paper›PMID 38233523›Full record

ArticleNature2024

Alternative splicing of latrophilin-3 controls synapse formation.

Shuai Wang, Chelsea DeLeon, Wenfei Sun, Stephen R Quake, Bryan L Roth, Thomas C Südhof

Open access · hybridAbstract read
In one paragraph

Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
11.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 52 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Review
  6. Adhesion G protein-coupled receptors.Pharmacological reviews · 2026
    Review
  7. EndothelialThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. MRAS: Master Regulator Analysis of Alternative Splicing.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Shuai WangDepartment of Molecular and Cellular Physiology, Stanford University, Stanford, CA, USA. swang9@stanford.edu.ORCID 0000-0002-8920-969X
Chelsea DeLeonDepartment of Pharmacology, UNC Chapel Hill School of Medicine, Chapel Hill, NC, USA.
Wenfei SunDepartment of Molecular and Cellular Physiology, Stanford University, Stanford, CA, USA.ORCID 0000-0001-5762-6010
Stephen R QuakeDepartment of Applied Physics, Stanford University, Stanford, CA, USA.ORCID 0000-0002-1613-0809
Bryan L RothDepartment of Pharmacology, UNC Chapel Hill School of Medicine, Chapel Hill, NC, USA.ORCID 0000-0002-0561-6520
Thomas C SüdhofDepartment of Molecular and Cellular Physiology, Stanford University, Stanford, CA, USA. tcs1@stanford.edu.ORCID 0000-0003-3361-9275
Howard Hughes Medical Institute · USUniversity of North Carolina at Chapel Hill · USChan Zuckerberg Initiative (United States) · USStanford University · US

Funding

Illuminating the Druggable GPCR-omeU24DK116195 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ROTH, BRYAN L., SHOICHET, BRIAN K · 2017 to 2022
$14.3M
Latrophilin Function in Synapse FormationR01MH126929 · NIMH · STANFORD UNIVERSITY · PI Thomas C. Sudhof · 2021 to 2026
$4.3M
NIDDK NIH HHS U24 DK116195NIMH NIH HHS R01 MH126929
6 · The paper itself

Abstract

The assembly and specification of synapses in the brain is incompletely understood

Indexed as

Alternative SplicingReceptors, G-Protein-CoupledReceptors, PeptideSynapsesAnimalsChromograninsGTP-Binding Protein alpha Subunits, G12-G13GTP-Binding Protein alpha Subunits, GsLigandsMiceNerve Tissue ProteinsSignal TransductionTenascinAdgrl3 protein, mousealpha-latrotoxin receptorChromograninsGnas protein, mouseGTP-Binding Protein alpha Subunits, G12-G13GTP-Binding Protein alpha Subunits, GsLigandsNerve Tissue ProteinsReceptors, G-Protein-CoupledReceptors, PeptideTenascinteneurin-1

Identifiers

PMID38233523
PMCPMC10830413
OpenAlexW4390940940

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.