Evidence map›Paper›PMID 38233522›Full record

ArticleNature2024

Top-down control of flight by a non-canonical cortico-amygdala pathway.

Chandrashekhar D Borkar, Claire E Stelly, Xin Fu, Maria Dorofeikova, Quan-Son Eric Le, Rithvik Vutukuri, Catherine Vo, Alice Breaux Walker, Samhita Basavanhalli, Anh Duong and 5 more

Open access · greenAbstract read
In one paragraph

Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
12.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
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  14. Dorsal-Caudal and Ventral Hippocampi Target Different Cell Populations in the Medial Frontal Cortex in Rodents.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  15. Article
  16. Hypothalamic Control of Learned Flight Induced by Threat Imminence.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  17. Review
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Chandrashekhar D BorkarDepartment of Psychology, Tulane University, New Orleans, LA, USA.
Claire E StellyDepartment of Psychology, Tulane University, New Orleans, LA, USA.
Xin FuTulane Brain Institute, Tulane University, New Orleans, LA, USA.
Maria DorofeikovaDepartment of Psychology, Tulane University, New Orleans, LA, USA.
Quan-Son Eric LeTulane Brain Institute, Tulane University, New Orleans, LA, USA.
Rithvik VutukuriTulane Brain Institute, Tulane University, New Orleans, LA, USA.ORCID 0000-0003-2498-4377
Catherine VoTulane Brain Institute, Tulane University, New Orleans, LA, USA.
Alice Breaux WalkerTulane Brain Institute, Tulane University, New Orleans, LA, USA.
Samhita BasavanhalliTulane Brain Institute, Tulane University, New Orleans, LA, USA.
Anh DuongTulane Brain Institute, Tulane University, New Orleans, LA, USA.
Erin BeanTulane Brain Institute, Tulane University, New Orleans, LA, USA.
Alexis ResendezDepartment of Psychology, Tulane University, New Orleans, LA, USA.
Jones G ParkerDepartment of Neuroscience, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.ORCID 0000-0001-9302-1545
Jeffrey G TaskerTulane Brain Institute, Tulane University, New Orleans, LA, USA.
Jonathan P FadokDepartment of Psychology, Tulane University, New Orleans, LA, USA. jfadok@tulane.edu.ORCID 0000-0002-0608-5151
Tulane University · USNorthwestern University · US

Funding

Stress Plasticity of CRH NeuronsR01MH119283 · NIMH · TULANE UNIVERSITY OF LOUISIANA · PI TASKER, JEFFREY G · 2019 to 2025
$2.7M
Neural circuits regulating flight and panic behavior.R01MH122561 · NIMH · TULANE UNIVERSITY OF LOUISIANA · PI FADOK, JONATHAN P · 2020 to 2024
$2.4M
Dopamine, Synaptic Plasticity and Striatal Ensemble Dynamics Underlying Motor LearningR01NS122840 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI PARKER, JONES G · 2021 to 2025
$2.2M
NIMH NIH HHS R01 MH119283NIMH NIH HHS R01 MH122561NINDS NIH HHS R01 NS122840
6 · The paper itself

Abstract

Survival requires the selection of appropriate behaviour in response to threats, and dysregulated defensive reactions are associated with psychiatric illnesses such as post-traumatic stress and panic disorder

Indexed as

Avoidance LearningCentral Amygdaloid NucleusNeural PathwaysNeuronsCalciumElectrophysiologyExcitatory Amino Acid AgentsGlutamic AcidPonsPrefrontal CortexCalciumExcitatory Amino Acid AgentsGlutamic Acid

Identifiers

PMID38233522
PMCPMC10878556
OpenAlexW4390940935

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.