ArticleCommunications biology2024
Genome-wide association identifies novel ROP risk loci in a multiethnic cohort.
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Article in Communications biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
What it found
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Who cites it
5 citing papers in PubMed, 6 citations in OpenAlex.
- New Genetic Associations Between Alzheimer's Disease and Its Key Risk Factors.Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society · 2026Article
- Race, oxygen exposure, and retinopathy of prematurity: re-examining a persistent epidemiologic paradox.Experimental biology and medicine (Maywood, N.J.) · 2026Review
- Involving neonatal hematology and transfusion medicine in global efforts to eliminate severe retinopathy of prematurity.Journal of perinatology : official journal of the California Perinatal Association · 2025Review
- Association of the ADRB2 rs1042714 variant with retinopathy of prematurity highlights the importance of the renin-angiotensin-aldosterone system.Scientific reports · 2025Article
- Genetic risk and retinopathy of prematurity: homing in on a target?Pediatric research · 2024Article
Corrections and comments
- Update of
Authors and funding
18 authors at 15 institutions in 2 countries.
Xiaohui Li *Institute for Translational Genomics and Population Sciences, The Lundquist Institute for Biomedical Innovation; Department of Pediatrics, Harbor-UCLA Medical Center, Torrance, CA, USA.
Leah A Owen *Department of Ophthalmology and Visual Sciences, University of Utah, Salt Lake City, UT, USA. Leah.owen@hsc.utah.edu.ORCID 0000-0003-3802-3868
Kent D TaylorInstitute for Translational Genomics and Population Sciences, The Lundquist Institute for Biomedical Innovation; Department of Pediatrics, Harbor-UCLA Medical Center, Torrance, CA, USA.
Susan OstmoCasey Eye Institute, Oregon Health & Science University, Portland, OR, USA.
Yii-Der Ida ChenInstitute for Translational Genomics and Population Sciences, The Lundquist Institute for Biomedical Innovation; Department of Pediatrics, Harbor-UCLA Medical Center, Torrance, CA, USA.ORCID 0000-0003-1741-3517
Aaron S CoynerCasey Eye Institute, Oregon Health & Science University, Portland, OR, USA.ORCID 0000-0003-3261-1909
Kemal SonmezCasey Eye Institute, Oregon Health & Science University, Portland, OR, USA.
M Elizabeth HartnettByers Eye Institute at Stanford University, Palo Alto, CA, USA.
Xiuqing GuoInstitute for Translational Genomics and Population Sciences, The Lundquist Institute for Biomedical Innovation; Department of Pediatrics, Harbor-UCLA Medical Center, Torrance, CA, USA.ORCID 0000-0002-5264-5068
Eli IppDivision of Endocrinology and Metabolism, Department of Medicine, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA.ORCID 0000-0003-1588-0146
Kathryn RollInstitute for Translational Genomics and Population Sciences, The Lundquist Institute for Biomedical Innovation; Department of Pediatrics, Harbor-UCLA Medical Center, Torrance, CA, USA.
Pauline GenterDivision of Endocrinology and Metabolism, Department of Medicine, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA.
R V Paul ChanDepartment of Ophthalmology and Visual Sciences, Illinois Eye and Ear Infirmary, University of Illinois at Chicago, Chicago, IL, USA.ORCID 0000-0002-1971-2249
Margaret M DeAngelisInstitute for Translational Genomics and Population Sciences, The Lundquist Institute for Biomedical Innovation; Department of Pediatrics, Harbor-UCLA Medical Center, Torrance, CA, USA.
Michael F ChiangNational Eye Institute, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0002-8172-7636
J Peter CampbellCasey Eye Institute, Oregon Health & Science University, Portland, OR, USA. campbelp@ohsu.edu.ORCID 0000-0001-7964-9475
Jerome I RotterInstitute for Translational Genomics and Population Sciences, The Lundquist Institute for Biomedical Innovation; Department of Pediatrics, Harbor-UCLA Medical Center, Torrance, CA, USA. jrotter@lundquist.org.ORCID 0000-0001-7191-1723
i-ROP Consortium
UCLA Medical Center · USOregon Health & Science University · USAsociacion Para Evitar la Ceguera en México Hospital Dr. Luis Sánchez Bulnes · MXChildren's Hospital of Los Angeles · USBeaumont Hospital, Royal Oak · USColumbia University · USPalo Alto University · USUniversity of Illinois Chicago · USUniversity of Utah · USCedars-Sinai Medical Center · USNational Institutes of Health · USNortheastern University · USCornell University · USMassachusetts General Hospital · USSmith-Kettlewell Eye Research Institute · US
Funding
UCLA Clinical Translational Science InstituteUL1TR001881 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ARLEEN F. BROWN, ARASH NAEIM · 2016 to 2026
$118.1MTransgenic & Knock-out MouseP30DK063491 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI PETER J TONTONOZ · 2003 to 2026
$40.4MProteomics CoreP30EY010572 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI TED S ACOTT · 1995 to 2026
$19.4MUniversity of Utah, Core Vision Research GrantP30EY014800 · NEI · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI PAUL STEVEN BERNSTEIN · 2005 to 2026
$14.6MCHARGE Consortium: Omics Discovery for CVD and Aging PhenotypesR01HL105756 · NHLBI · UNIVERSITY OF WASHINGTON · PI Bruce M Psaty, NICHOLAS L SMITH · 2011 to 2026
$9.5MMechanisms of Angiogenesis of Retinopathy of PrematurityR01EY015130 · NEI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Mary Elizabeth Ruth Hartnett · 2005 to 2026
$7.6MClinical and Genetic Analysis of Retinopathy of PrematurityR01EY019474 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI CAMPBELL, JOHN PETER · 2010 to 2020
$7.0MGenetics of Diabetic Retinopathy in HispanicsR01EY014684 · NEI · CEDARS-SINAI MEDICAL CENTER · PI ROTTER, JEROME I · 2004 to 2011
$4.4MSystems-Biology Analysis of Mechanisms Informing Preeclampsia-Mediated ROP ProtectionK08EY031800 · NEI · UNIVERSITY OF UTAH · PI OWEN, LEAH A · 2020 to 2022
$497kRobust AI to develop risk models in retinopathy of prematurity using deep learningR21EY031883 · NEI · MASSACHUSETTS GENERAL HOSPITAL · PI KALPATHY-CRAMER, JAYASHREE, RUBIN, DANIEL L · 2020 to 2021
$472kA Phase 2 Study of the Value of Pre-symptomatic Genetic Risk Assessment for Age-Related Macular DegenerationR21EY033579 · NEI · UNIVERSITY OF UTAH · PI BERNSTEIN, PAUL STEVEN, HARTNETT, MARY ELIZABETH RUTH · 2022 to 2023
$423kArtificial intelligence assisted panoramic Optical Coherence Tomography Angiography for Retinopathy of PrematurityR01EY031331 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI CAMPBELL, JOHN PETER, JIAN, YIFAN · 2020 to 2020
$342kNCATS NIH HHS UL1 TR001881NEI NIH HHS K08 EY031800NEI NIH HHS P30 EY010572NEI NIH HHS P30 EY014800NEI NIH HHS R01 EY014684NEI NIH HHS R01 EY015130NEI NIH HHS R01 EY019474NEI NIH HHS R01 EY031331NEI NIH HHS R21 EY031883NEI NIH HHS R21 EY033579NHLBI NIH HHS R01 HL105756NIDDK NIH HHS P30 DK063491
Abstract
We conducted a genome-wide association study (GWAS) in a multiethnic cohort of 920 at-risk infants for retinopathy of prematurity (ROP), a major cause of childhood blindness, identifying 1 locus at genome-wide significance level (p < 5×10
Indexed as
Genome-Wide Association StudyRetinopathy of PrematurityEthnicityGenetic Predisposition to DiseaseHumansInfant, NewbornPolymorphism, Single Nucleotide
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