Evidence map›Paper›PMID 38233463›Full record

ArticleLeukemia2024

OST-01, a natural product from Baccharis coridifolia, targets c-Myc-dependent ribogenesis in acute myeloid leukemia.

HyunJun Kang, Dinh Hoa Hoang, Melissa Valerio, Khyatiben Pathak, Lianjun Zhang, Ralf Buettner, Fang Chen, Katrina Estrella, William Graff, Zhuo Li and 7 more

Open access · hybridAbstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Leukemia, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 2 institutions in 1 country.

HyunJun Kang *Department of Hematologic Malignancies Translational Science, Beckman Research Institute and City of Hope National Medical Center, Duarte, CA, USA.
Dinh Hoa Hoang *Department of Hematologic Malignancies Translational Science, Beckman Research Institute and City of Hope National Medical Center, Duarte, CA, USA.
Melissa Valerio *Department of Hematologic Malignancies Translational Science, Beckman Research Institute and City of Hope National Medical Center, Duarte, CA, USA.
Khyatiben PathakCancer & Cell Biology Division, Translational Genomics Research Institute, Phoenix, AZ, USA.
Lianjun ZhangDepartment of Hematologic Malignancies Translational Science, Beckman Research Institute and City of Hope National Medical Center, Duarte, CA, USA.
Ralf BuettnerDepartment of Hematologic Malignancies Translational Science, Beckman Research Institute and City of Hope National Medical Center, Duarte, CA, USA.
Fang ChenDepartment of Hematologic Malignancies Translational Science, Beckman Research Institute and City of Hope National Medical Center, Duarte, CA, USA.ORCID http://orcid.org/0000-0002-8871-2752
Katrina EstrellaDepartment of Hematologic Malignancies Translational Science, Beckman Research Institute and City of Hope National Medical Center, Duarte, CA, USA.ORCID http://orcid.org/0009-0003-0418-8741
William GraffOstentus Therapeutics, Inc., Newport Coast, CA, USA.
Zhuo LiBeckman Research Institute, City of Hope National Medical Center, Duarte, CA, USA.
Jun XieDepartment of Molecular Medicine, City of Hope National Medical Center, Duarte, CA, USA.
David HorneDepartment of Molecular Medicine, City of Hope National Medical Center, Duarte, CA, USA.ORCID http://orcid.org/0000-0002-9300-1082
Ya-Huei KuoDepartment of Hematologic Malignancies Translational Science, Beckman Research Institute and City of Hope National Medical Center, Duarte, CA, USA.ORCID http://orcid.org/0000-0003-2595-0419
Bin ZhangDepartment of Hematologic Malignancies Translational Science, Beckman Research Institute and City of Hope National Medical Center, Duarte, CA, USA.ORCID http://orcid.org/0000-0003-4703-7524
Patrick PirrotteCancer & Cell Biology Division, Translational Genomics Research Institute, Phoenix, AZ, USA.
Le Xuan Truong NguyenDepartment of Hematologic Malignancies Translational Science, Beckman Research Institute and City of Hope National Medical Center, Duarte, CA, USA. lenguyen@coh.org.
Guido MarcucciDepartment of Hematologic Malignancies Translational Science, Beckman Research Institute and City of Hope National Medical Center, Duarte, CA, USA. gmarcucci@coh.org.ORCID http://orcid.org/0000-0002-3983-5908
City Of Hope National Medical Center · USTranslational Genomics Research Institute · US

Funding

Transgenic Mouse FacilityP30CA033572 · NCI · CITY OF HOPE/BECKMAN RESEARCH INSTITUTE · PI John Charles Williams · 1985 to 2026
$86.3M
NCI NIH HHS P30 CA033572
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

BaccharisBiological ProductsLeukemia, Myeloid, AcuteHumansProto-Oncogene Proteins c-mycBiological ProductsProto-Oncogene Proteins c-myc

Identifiers

PMID38233463
PMCPMC10912030
OpenAlexW4390947672

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.