Evidence map›Paper›PMID 38233280›Full record

Trial reportSleep health2024

The effects of insufficient sleep and adequate sleep on cognitive function in healthy adults.

Molly E Zimmerman, Giada Benasi, Christiane Hale, Lok-Kin Yeung, Justin Cochran, Adam M Brickman, Marie-Pierre St-Onge

3 registry-linked trialsAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Sleep health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 44 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02835261 nacompletednot on this map

Impact of Sleep Restriction on Cardiometabolic Risk Factors in Pre vs Postmenopausal Women

TypeinterventionalSponsorColumbia UniversityRan2016 to 2021Enrolled54ConditionsSleep, Cardiovascular Disease, ObesityArmsSleep Restriction
NCT02960776 nacompletednot on this map

Effect of Long Term Sleep Restriction on Energy Balance

TypeinterventionalSponsorColumbia UniversityRan2016 to 2023Enrolled45ConditionsSleep, Obesity, Sleep RestrictionArmsSleep Restriction (SR)
NCT07589114 narecruitingnot on this mapstarted 2025, after this paper: background citation

REM Enhancement Sleep Technology for Well-being, Emotion, and Life Lift

TypeinterventionalSponsorGeorge Emil Palade University of Medicine, Pharmacy, Sciences and Technology of Targu MuresRan2025 to 2027Enrolled360ConditionsHealthy Adult ParticipantsArmsMobile smartwatch application.
3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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  8. Association between sleep inertia and cognitive performance among older adults in the Wisconsin Sleep Cohort study.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Molly E ZimmermanFordham University, Department of Psychology, Bronx, New York, USA. Electronic address: mzimmerman7@fordham.edu.
Giada BenasiDivision of General Medicine, Department of Medicine, Columbia University Irving Medical Center, New York, New York, USA.
Christiane HaleTaub Institute for Research on Alzheimer's Disease and the Aging Brain, Vagelos College of Physicians and Surgeons, Columbia University, New York, New York, USA.
Lok-Kin YeungTaub Institute for Research on Alzheimer's Disease and the Aging Brain, Vagelos College of Physicians and Surgeons, Columbia University, New York, New York, USA.
Justin CochranCenter of Excellence for Sleep & Circadian Research and Division of General Medicine, Department of Medicine, Columbia University Vagelos College of Physicians and Surgeons, New York, New York, USA.
Adam M BrickmanTaub Institute for Research on Alzheimer's Disease and the Aging Brain, Vagelos College of Physicians and Surgeons, Columbia University, New York, New York, USA; Department of Neurology, Vagelos College of Physicians and Surgeons, Columbia University, New York, New York, USA.
Marie-Pierre St-OngeDivision of General Medicine, Department of Medicine, Columbia University Irving Medical Center, New York, New York, USA; Center of Excellence for Sleep & Circadian Research and Division of General Medicine, Department of Medicine, Columbia University Vagelos College of Physicians and Surgeons, New York, New York, USA. Electronic address: ms2554@cumc.columbia.edu.

Funding

Mechanisms addressing the causal relationships of sleep, circadian rhythms, and cardiometabolic healthR35HL155670 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MARIE-PIERRE ST-ONGE · 2021 to 2026
$5.4M
OBESITY RESEARCH CENTER TRAINING PROGRAMT32DK007559 · NIDDK · ST. LUKE'S-ROOSEVELT INST FOR HLTH SCIS · PI DYMPNA GALLAGHER · 1989 to 2026
$4.3M
Effect of long-term sleep restriction on energy balanceR01HL128226 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI ST-ONGE, MARIE-PIERRE · 2016 to 2019
$3.4M
NHLBI NIH HHS R01 HL128226NHLBI NIH HHS R35 HL155670NIDDK NIH HHS T32 DK007559
6 · The paper itself

Abstract

STUDY

objectivesAlthough sleep affects a range of waking behaviors, the majority of studies have focused on sleep loss with relatively little attention on sustained periods of adequate sleep. The goal of this study was to use an experimental design to examine the effect of both of these sleep patterns on cognitive performance in healthy adults.

methodsThis study used a randomized crossover design. Participants who regularly slept 7-9 hours/night completed two 6-week intervention conditions, adequate sleep (maintenance of habitual bed/wake times) and insufficient sleep (reduction in sleep of 1.5 hours relative to adequate sleep), separated by a 2-6weeks (median=43days) washout period. Cognitive functioning was evaluated at baseline and endpoint of each intervention using the NIH Toolbox Cognition Battery. General linear models contrasted scores following each condition to the baseline of the first condition; the baseline of the second condition was included to evaluate practice effects.

resultsSixty-five participants (age 35.9 ± 4.9years, 89% women, 52% non-White race/ethnicity) completed study procedures. There was improvement in performance on the List Sorting Working Memory task after the adequate sleep condition that exceeded practice effects. Cognitive performance after insufficient sleep did not reach the level expected with practice and did not differ from baseline. A similar pattern was found on the Flanker Inhibitory Control and Attention task.

conclusionsThese findings contribute to our understanding of the complex interplay between sleep and cognition and demonstrate that consistent, stable sleep of at least 7 hours/night improves working memory and response inhibition in healthy adults. CLINICAL

trial registrationThe manuscript reports on data from two clinical trials: Impact of Sleep Restriction on Performance in Adults (URL: https://clinicaltrials.gov/ct2/show/NCT02960776, ID Number: NCT02960776) and Impact of Sleep Restriction in Women (URL: https://clinicaltrials.gov/ct2/show/NCT02835261, ID Number: NCT02835261).

Indexed as

CognitionCross-Over StudiesSleepAdultFemaleHumansMaleSleep DeprivationAdequate sleepCognitionInsufficient sleepSleep restrictionStable sleepWorking memory

Identifiers

PMID38233280
PMCPMC11045317

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.