Evidence map›Paper›PMID 38233077›Full record

Observational studyBMJ open diabetes research & care2024

Increased glycemic variability in pregnant women with Roux-en-Y gastric bypass compared with sleeve gastrectomy.

Kleopatra Alexiadou, Saleem Ansari, Bryony Jones, Christina Yu, Anne Dornhorst, Nick Oliver, Christos Tsironis, Sanjay Purkayastha, Ahmed Ahmed, Rochan Agha-Jaffar and 2 more

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in BMJ open diabetes research & care, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.3field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Perinatal Outcomes After Sleeve Gastrectomy Compared to a Matched Control Group.The Australian & New Zealand journal of obstetrics & gynaecology · 2026
    Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Kleopatra Alexiadou *Department of Metabolism Digestion and Reproduction, Imperial College London, London, UK.
Saleem Ansari *Department of Metabolism Digestion and Reproduction, Imperial College London, London, UK.
Bryony JonesQueen Charlotte's and Chelsea Hospital, London, UK.
Christina YuQueen Charlotte's and Chelsea Hospital, London, UK.
Anne DornhorstDepartment of Metabolism Digestion and Reproduction, Imperial College London, London, UK.
Nick OliverDepartment of Metabolism Digestion and Reproduction, Imperial College London, London, UK.
Christos TsironisSurgery and Cancer, Imperial College Healthcare NHS Trust, London, UK.
Sanjay PurkayasthaSurgery and Cancer, Imperial College Healthcare NHS Trust, London, UK.
Ahmed AhmedSurgery and Cancer, Imperial College Healthcare NHS Trust, London, UK.
Rochan Agha-JaffarDepartment of Metabolism Digestion and Reproduction, Imperial College London, London, UK.
Bernard KhooDivision of Medicine, University College London, London, UK.ORCID 0000-0002-4223-9736
Tricia M-M TanDepartment of Metabolism Digestion and Reproduction, Imperial College London, London, UK t.tan@imperial.ac.uk.ORCID 0000-0001-5873-3432
Imperial College London · GBImperial College Healthcare NHS Trust · GBQueen Charlotte's and Chelsea Hospital · GBUniversity College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionBariatric surgery is associated with adverse pregnancy outcomes such as reduced birth weight and premature birth. One possible mechanism for this is increased glycemic variability (GV) which occurs after bariatric surgery. The objective of this study was to compare the effect of Roux-en-Y gastric bypass (RYGB) versus vertical sleeve gastrectomy (SG) on GV during pregnancy and to investigate the relationships of GV, type of bariatric surgery and maternal and neonatal outcomes. RESEARCH DESIGN AND

methodsFourteen pregnant women after RYGB and 14 after SG were investigated with continuous glucose monitoring in their second or third trimester in this observational study carried out as part of routine clinical care.

resultsPregnant women with RYGB had similar mean interstitial glucose values but significantly increased indices of GV and a lower %time in range 3.9-7.8 mmol/L (70-140 mg/dL), compared with SG.

conclusionsPregnant women who have undergone RYGB have greater GV during pregnancy compared with those who have undergone SG. Further research is needed to establish the relationship between GV and pregnancy outcomes to determine the preferred bariatric operation in women of reproductive age, and whether interventions to reduce GV might improve outcomes.

Indexed as

Gastric BypassBlood GlucoseBlood Glucose Self-MonitoringFemaleGastrectomyHumansInfant, NewbornPregnancyPregnancy OutcomePregnant PeopleBlood Glucosebariatric surgerypregnancy

Identifiers

PMID38233077
PMCPMC10806855
OpenAlexW4390945873

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.