ArticleBMJ (Clinical research ed.)2024
All cause and cause specific mortality in obsessive-compulsive disorder: nationwide matched cohort and sibling cohort study.
Article in BMJ (Clinical research ed.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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Who cites it
22 citing papers in PubMed, 33 citations in OpenAlex.
- Predicting six month follow-up of suicidal thoughts and attempts among youth with anxiety presenting to an emergency department.JCPP advances · 2026Article
- Advancements in the Understanding of the Genetics of Obsessive-Compulsive Disorder (OCD).Current psychiatry reports · 2026Review
- Are There Causal Associations Between Obsessive-Compulsive Disorder and Cardiometabolic Phenotypes? A Genetic Correlation and Bi-Directional Mendelian Randomization Study.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics · 2026Article
- Vitamin D Deficiency and Obsessive-Compulsive Disorder Severity: A Cross-Sectional Study.Life (Basel, Switzerland) · 2026Article
- All-Cause and Cause-Specific Mortality in Patients With Bipolar II Disorder.JAMA network open · 2026Observational
- All-cause and cause-specific mortality in social anxiety disorder: a matched cohort and sibling cohort study.Epidemiology and psychiatric sciences · 2026Article
- Lifestyle habits and use of general medical services among individuals with obsessive-compulsive disorder: a qualitative study.BMC psychiatry · 2026Article
- Prevention of Obsessive-Compulsive Disorder in At-Risk Children: A Feasibility Trial.Child psychiatry and human development · 2026Article
- Post-traumatic stress disorder and risk of all-cause and cause-specific mortality: a nationwide population and sibling-controlled cohort study in Taiwan.Epidemiology and psychiatric sciences · 2026Article
- Recommended Medical Investigations in Pediatric Acute-Onset Neuropsychiatric Syndrome.JAMA network open · 2026Article
- The PADRIS-PRESTO cohort: A comprehensive population-based study on mental health in Catalonia.European psychiatry : the journal of the Association of European Psychiatrists · 2025Article
- Exploring Applications of Transcranial Magnetic Stimulation in Child and Adolescent Psychiatry: A Narrative Review.Journal of clinical medicine · 2025Review
- A structured lifestyle intervention to reduce cardiometabolic risk factors in individuals with obsessive-compulsive disorder: feasibility trial.BJPsych open · 2025Article
- Help-seeking behavior, treatment barriers and facilitators, attitudes and access to first-line treatment in German adults with obsessive-compulsive disorder.BMC psychiatry · 2025Article
- All-Cause and Cause-Specific Mortality in Tourette Syndrome and Chronic Tic Disorder.Movement disorders : official journal of the Movement Disorder Society · 2025Article
- Multigenerational family coaggregation study of obsessive-compulsive disorder and cardiometabolic disorders.BMJ mental health · 2025Article
- Risk of self-harm in patients with body dysmorphic disorder: a population-based cohort study.Frontiers in psychiatry · 2025Article
- Sociodemographic, mental health, education, employment and income characteristics of adults with obsessive-compulsive disorder who accessed secondary health services in Aotearoa | New Zealand.Journal of the Royal Society of New Zealand · 2025Article
- Body dysmorphic disorder.Nature reviews. Disease primers · 2024Review
- The association between salivary oxytocin, age, and puberty in children with and without OCD.Scientific reports · 2024Article
Corrections and comments
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Authors and funding
11 authors at 4 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo estimate the risk of all cause and cause specific mortality in people with obsessive-compulsive disorder (OCD) compared with matched unaffected people from the general population and with their unaffected siblings.
designPopulation based matched cohort and sibling cohort study.
settingRegister linkage in Sweden.
participantsPopulation based cohort including 61 378 people with OCD and 613 780 unaffected people matched (1:10) on sex, birth year, and county of residence; sibling cohort consisting of 34 085 people with OCD and 47 874 unaffected full siblings. Cohorts were followed up for a median time of 8.1 years during the period from 1 January 1973 to 31 December 2020.
main outcome measuresAll cause and cause specific mortality.
results4787 people with OCD and 30 619 unaffected people died during the study period (crude mortality rate 8.1 and 5.1 per 1000 person years, respectively). In stratified Cox proportional hazards models adjusted for birth year, sex, county, migrant status (born in Sweden versus abroad), and sociodemographic variables (latest recorded education, civil status, and family income), people with OCD had an increased risk of all cause mortality (hazard ratio 1.82, 95% confidence interval 1.76 to 1.89) and mortality due to natural causes (1.31, 1.27 to 1.37) and unnatural causes (3.30, 3.05 to 3.57). Among the natural causes of death, those due to endocrine, nutritional, and metabolic diseases, mental and behavioural disorders, and diseases of the nervous, circulatory, respiratory, digestive, and genitourinary systems were higher in the OCD cohort. Conversely, the risk of death due to neoplasms was lower in the OCD cohort compared with the unaffected cohort. Among the unnatural causes, suicide showed the highest hazard ratio, followed by accidents. The results were robust to adjustment for psychiatric comorbidities and familial confounding.
conclusionsNon-communicable diseases and external causes of death, including suicides and accidents, were major contributors to the risk of mortality in people with OCD. Better surveillance, prevention, and early intervention strategies should be implemented to reduce the risk of fatal outcomes in people with OCD.
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