Evidence map›Paper›PMID 38232692›Full record

ArticleCell reports. Medicine2024

Very-low-density lipoprotein triglyceride and free fatty acid plasma kinetics in women with high or low brown adipose tissue volume and overweight/obesity.

Maria Chondronikola, Jun Yoshino, Raja Ramaswamy, Joseph Daniel Giardina, Richard Laforest, Richard L Wahl, Bruce W Patterson, Bettina Mittendorfer, Samuel Klein

Open access · goldAbstract read
In one paragraph

Article in Cell reports. Medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Macrophages in metaflammation - fueling chronic inflammation in metabolic disease.Pflugers Archiv : European journal of physiology · 2025
    Review
  3. Review
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 3 countries.

Maria ChondronikolaCenter for Human Nutrition, Washington University School of Medicine, St. Louis, MO, USA; Wellcome-MRC Institute of Metabolic Science-Metabolic Research Laboratories, Medical Research Council Metabolic Diseases Unit, University of Cambridge, Cambridge, UK; Department of Nutritional Sciences and Dietetics, Harokopio University of Athens, Kallithea, Greece. Electronic address: mc2425@medschl.cam.ac.uk.
Jun YoshinoCenter for Human Nutrition, Washington University School of Medicine, St. Louis, MO, USA.
Raja RamaswamyDepartment of Radiology, Washington University School of Medicine, St. Louis, MO, USA.
Joseph Daniel GiardinaDepartment of Radiology, Washington University School of Medicine, St. Louis, MO, USA.
Richard LaforestDepartment of Radiology, Washington University School of Medicine, St. Louis, MO, USA.
Richard L WahlDepartment of Radiology, Washington University School of Medicine, St. Louis, MO, USA.
Bruce W PattersonCenter for Human Nutrition, Washington University School of Medicine, St. Louis, MO, USA.
Bettina MittendorferCenter for Human Nutrition, Washington University School of Medicine, St. Louis, MO, USA.
Samuel KleinCenter for Human Nutrition, Washington University School of Medicine, St. Louis, MO, USA; Sansum Diabetes Research Institute, Santa Barbara, CA, USA. Electronic address: sklein@wustl.edu.
Washington University in St. Louis · USUniversity of Cambridge · GB

Funding

WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
Washington University Nutrition Obesity Research CenterP30DK056341 · NIDDK · WASHINGTON UNIVERSITY · PI Brian N Finck · 1999 to 2026
$30.2M
WU P&FP30DK020579 · NIDDK · WASHINGTON UNIVERSITY · PI Jennifer Lynn Powers Carson · 2013 to 2026
$27.1M
NCATS NIH HHS UL1 TR002345NIDDK NIH HHS P30 DK020579NIDDK NIH HHS P30 DK056341Wellcome Trust
6 · The paper itself

Abstract

Although a high amount of brown adipose tissue (BAT) is associated with low plasma triglyceride concentration, the mechanism responsible for this relationship in people is not clear. Here, we evaluate the interrelationships among BAT, very-low-density lipoprotein triglyceride (VLDL-TG), and free fatty acid (FFA) plasma kinetics during thermoneutrality in women with overweight/obesity who had a low (<20 mL) or high (≥20 mL) volume of cold-activated BAT (assessed by using positron emission tomography in conjunction with 2-deoxy-2-[

Indexed as

Fatty Acids, NonesterifiedOverweightAdipose Tissue, BrownFemaleHumansLipoproteins, VLDLObesityTriglyceridesFatty Acids, NonesterifiedLipoproteins, VLDLTriglyceridesbrown fatfree fatty acidskineticslipidsmetabolismobesitytriglycerideswomen

Identifiers

PMID38232692
PMCPMC10829791
OpenAlexW4390988966

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.