ArticleJournal of the American Chemical Society2024
Alkene Hydrobenzylation by a Single Catalyst That Mediates Iterative Outer-Sphere Steps.
Article in Journal of the American Chemical Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Article
- Nickel-Catalyzed Radical-Radical Cross-Coupling Reactions.Chemistry (Weinheim an der Bergstrasse, Germany) · 2026Review
- Discovery of a phenazine-thiol conjugase from sparse data using genome-informed machine learning.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Dual Photoredox/Cobalt Catalysis Enabled Regiospecific Markovnikov Hydroboration of Unactivated Mono-, Di-, and Trisubstituted Alkenes.Nature communications · 2026Article
- A Dual Photoredox/Cobalt Catalytic System Enables Markovnikov-Selective Hydroaminoalkylation of Alkenes.Precision chemistry · 2026Article
- Quaternary Carbons from Amines and Acids.Journal of the American Chemical Society · 2026Article
- Deaminative C(Journal of the American Chemical Society · 2026Article
- Cross-ketone deacylative coupling via oxidative SNature communications · 2026Article
- Discovery of a phenazine-thiol conjugase from sparse data using genome-informed machine learning.bioRxiv : the preprint server for biology · 2026Article
- Article
- Bimolecular Homolytic Substitution (SACS central science · 2025Review
- Radical Sorting Catalysis via Bimolecular Homolytic Substitution (SJournal of the American Chemical Society · 2025Review
- Aminoalkylation of Alkenes Enabled by Triple Radical Sorting.Journal of the American Chemical Society · 2025Article
- Metal-Hydride C-C Cross-Coupling of Alkenes Through a Double Outer-Sphere Mechanism.The Journal of organic chemistry · 2024Review
- Iron-catalyzed radical Markovnikov hydrohalogenation and hydroazidation of alkenes.Nature communications · 2024Article
- 1,3-Difunctionalization of [1.1.1]propellane through iron-hydride catalyzed hydropyridylation.Nature communications · 2024Article
- Engaging Alkenes in Metallaphotoredox: A Triple Catalytic, Radical Sorting Approach to Olefin-Alcohol Cross-Coupling.Journal of the American Chemical Society · 2024Article
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Authors and funding
4 authors.
Funding
Abstract
Cross-coupling catalysts typically react and unite functionally distinct partners via sequential inner-sphere elementary steps: coordination, migratory insertion, reductive elimination, etc. Here, we report a single catalyst that cross-couples styrenes and benzyl bromides via iterative outer-sphere steps: metal-ligand-carbon interactions. Each partner forms a stabilized radical intermediate, yet heterocoupled products predominate. The system is redox-neutral and, thus, avoids exogenous oxidants, resulting in simple and scalable conditions. Numerous variations of alkene hydrobenzylation are made possible, including access to the privileged heterodibenzyl (1,2-diarylethane) motif and challenging quaternary carbon variants.
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