ArticleProceedings of the National Academy of Sciences of the United States of America2024
Quantifying local stiffness and forces in soft biological tissues using droplet optical microcavities.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Closing the Loop: High-Precision 3D Photofabrication in Living Tissues.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Liquid photonic-molecule microlasers for ultrasensitive biosensing.Nature communications · 2026Article
- Inline mechano-vibration holography for simultaneous phase and elasticity mapping of soft samples.Biomedical optics express · 2026Article
- Laser-emission vibrational microscopy of microdroplet arrays for high-throughput screening of hyperlipidemia.Light, science & applications · 2025Article
- Laser-emitting aqueous bioreactors for ultrasensitive bioactivity analysis.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- DNA Sensing with Whispering Gallery Mode Microlasers.Nano letters · 2025Article
- Quantifying local stiffness and forces in soft biological tissues using droplet optical microcavities.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- How growth-induced stresses guide shape changes during animal morphogenesis: Mechanisms and implications.Seminars in cell & developmental biologyReview
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Authors and funding
4 authors.
Funding
Abstract
Mechanical properties of biological tissues fundamentally underlie various biological processes and noncontact, local, and microscopic methods can provide fundamental insights. Here, we present an approach for quantifying the local mechanical properties of biological materials at the microscale, based on measuring the spectral shifts of the optical resonances in droplet microcavities. Specifically, the developed method allows for measurements of deformations in dye-doped oil droplets embedded in soft materials or biological tissues with an error of only 1 nm, which in turn enables measurements of anisotropic stress inside tissues as small as a few pN/μm
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Registered trials
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