Evidence map›Paper›PMID 38232180›Full record

ArticleChemical research in toxicology2024

Tissue Organoid Cultures Metabolize Dietary Carcinogens Proficiently and Are Effective Models for DNA Adduct Formation.

Angela L Caipa Garcia, Jill E Kucab, Halh Al-Serori, Rebekah S S Beck, Madjda Bellamri, Robert J Turesky, John D Groopman, Hayley E Francies, Mathew J Garnett, Meritxell Huch and 4 more

Open access · hybridAbstract read
In one paragraph

Article in Chemical research in toxicology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Organoids for Genotoxicity Assessment.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  5. Review
  6. Review
  7. A simple, efficient technique to make colon crypt gels for 3D models.3D printing and additive manufacturing · 2025
    Article
  8. Review
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 4 countries.

Angela L Caipa GarciaDepartment of Analytical, Environmental and Forensic Sciences, School of Cancer & Pharmaceutical Sciences, King's College London, London SE1 9NH, U.K.
Jill E KucabDepartment of Analytical, Environmental and Forensic Sciences, School of Cancer & Pharmaceutical Sciences, King's College London, London SE1 9NH, U.K.
Halh Al-SeroriDepartment of Analytical, Environmental and Forensic Sciences, School of Cancer & Pharmaceutical Sciences, King's College London, London SE1 9NH, U.K.
Rebekah S S BeckDepartment of Analytical, Environmental and Forensic Sciences, School of Cancer & Pharmaceutical Sciences, King's College London, London SE1 9NH, U.K.
Madjda BellamriDepartment of Medicinal Chemistry, Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota 55455, United States.
Robert J TureskyDepartment of Medicinal Chemistry, Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota 55455, United States.ORCID 0000-0001-7355-9903
John D GroopmanDepartment of Environmental Health and Engineering, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, United States.
Hayley E FranciesWellcome Sanger Institute, Cambridge CB10 1SA, U.K.
Mathew J GarnettWellcome Sanger Institute, Cambridge CB10 1SA, U.K.
Meritxell HuchMax Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany.
Jarno DrostPrincess Máxima Center for Pediatric Oncology, Oncode Institute, 3584 CS Utrecht, The Netherlands.
Matthias ZilbauerDepartment of Paediatrics, University of Cambridge, Cambridge CB2 0QQ, U.K.
Volker M ArltDepartment of Analytical, Environmental and Forensic Sciences, School of Cancer & Pharmaceutical Sciences, King's College London, London SE1 9NH, U.K.
David H PhillipsDepartment of Analytical, Environmental and Forensic Sciences, School of Cancer & Pharmaceutical Sciences, King's College London, London SE1 9NH, U.K.ORCID 0000-0001-8509-3485
King's College London · GBUniversity of Minnesota · USWellcome Sanger Institute · GBJohns Hopkins University · USMax Planck Institute of Molecular Cell Biology and Genetics · DEOncode Institute · NLUniversity of Cambridge · GB

Funding

Untargeted Analysis ResourceU2CES026533 · NIEHS · UNIVERSITY OF MINNESOTA · PI PETERSON, LISA A · 2015 to 2025
$14.0M
NIEHS NIH HHS U2C ES026533Wellcome Trust
6 · The paper itself

Abstract

Human tissue three-dimensional (3D) organoid cultures have the potential to reproduce

Indexed as

DNA AdductsNeoplasmsCarcinogensHumansLiverOrganoidsCarcinogensDNA Adducts

Identifiers

PMID38232180
PMCPMC10880098
OpenAlexW4390937992

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.