Evidence map›Paper›PMID 38231693›Full record

ArticleFoods (Basel, Switzerland)2023

Biosynthesis of Quercetin-Loaded Melanin Nanoparticles for Improved Antioxidant Activity, Photothermal Antimicrobial, and NIR/pH Dual-Responsive Drug Release.

Di Zhang, Xianrui Chen, Nitong Bu, Liying Huang, Huanglong Lin, Lizhen Zhou, Ruojun Mu, Lin Wang, Jie Pang

Abstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Di ZhangCollege of Food Science, Fujian Agriculture and Forestry University, Fuzhou 350002, China.
Xianrui ChenCollege of Food Science, Fujian Agriculture and Forestry University, Fuzhou 350002, China.
Nitong BuCollege of Food Science, Fujian Agriculture and Forestry University, Fuzhou 350002, China.
Liying HuangCollege of Food Science, Fujian Agriculture and Forestry University, Fuzhou 350002, China.
Huanglong LinCollege of Food Science, Fujian Agriculture and Forestry University, Fuzhou 350002, China.
Lizhen ZhouCollege of Food Science, Fujian Agriculture and Forestry University, Fuzhou 350002, China.
Ruojun MuCollege of Food Science, Fujian Agriculture and Forestry University, Fuzhou 350002, China.ORCID 0000-0003-2203-3121
Lin WangDepartment of Engineering Mechanics, Tsinghua University, Beijing 100084, China.
Jie PangCollege of Food Science, Fujian Agriculture and Forestry University, Fuzhou 350002, China.

Funding

China Postdoctoral Science Foundation 2022M712180Key project of Natural Science Foundation of Fujian Province 2022J02021Natural Science Foundation from Fujian Provincial Department of Science and Technology 2020J01556Scientific Research Foundation for Distinguished Young Scientists from Fujian Agriculture and Forestry University xjq202006
6 · The paper itself

Abstract

Quercetin (QCT) is a promising dose-dependent nutraceutical that usually suffers from poor water solubility and low bioavailability issues. In this work, a novel QCT-loaded nanoscale delivery system was constructed based on the oxidative self-polymerization of melanin (Q@MNPs). The FT-IR, XRD, and Zeta potential analyses confirmed that QCT was successfully absorbed on the melanin nanoparticles (MNPs) via Π-Π and hydrogen bonding interactions. The encapsulation efficiency and particle size of Q@MNPs were 43.78% and 26.68 nm, respectively. Q@MNPs improved the thermal stability of QCT and the antioxidant properties in comparison to MNPs. Meanwhile, Q@MNPs presented fantastic photothermal conversion capacity and stability triggered by the NIR laser, which significantly enhanced the antibacterial capability with a sterilization rate of more than 98% against

Indexed as

antioxidant activitymelanin nanoparticlesphotothermal antimicrobialquercetinstimuli drug release

Identifiers

PMID38231693
PMCPMC10706268

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.