Evidence map›Paper›PMID 38231564›Full record

ArticleACS applied materials & interfaces2024

Porous Laser-Scribed Graphene Electrodes Modified with Zwitterionic Moieties: A Strategy for Antibiofouling and Low-Impedance Interfaces.

Alanis C Zambrano, Livia M D Loiola, Abdullah Bukhamsin, Radoslaw Gorecki, George Harrison, Veerappan Mani, Shadi Fatayer, Suzana P Nunes, Khaled N Salama

Abstract read
In one paragraph

Article in ACS applied materials & interfaces, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alanis C ZambranoBioengineering Program, Biological and Environmental Sciences and Engineering Division, King Abdullah University of Science and Technology (KAUST), 23955-6900 Thuwal, Saudi Arabia.ORCID 0000-0003-3599-3930
Livia M D LoiolaAdvanced Membranes and Porous Materials Center, King Abdullah University of Science and Technology (KAUST), 23955-6900 Thuwal, Saudi Arabia.
Abdullah BukhamsinBioengineering Program, Biological and Environmental Sciences and Engineering Division, King Abdullah University of Science and Technology (KAUST), 23955-6900 Thuwal, Saudi Arabia.ORCID 0000-0002-3266-9628
Radoslaw GoreckiAdvanced Membranes and Porous Materials Center, King Abdullah University of Science and Technology (KAUST), 23955-6900 Thuwal, Saudi Arabia.ORCID 0000-0003-0149-6880
George HarrisonKAUST Solar Center, King Abdullah University of Science and Technology (KAUST), 23955-6900 Thuwal, Saudi Arabia.
Veerappan ManiAdvanced Membranes and Porous Materials Center, King Abdullah University of Science and Technology (KAUST), 23955-6900 Thuwal, Saudi Arabia.ORCID 0000-0002-0756-7398
Shadi FatayerKAUST Solar Center, King Abdullah University of Science and Technology (KAUST), 23955-6900 Thuwal, Saudi Arabia.
Suzana P NunesAdvanced Membranes and Porous Materials Center, King Abdullah University of Science and Technology (KAUST), 23955-6900 Thuwal, Saudi Arabia.
Khaled N SalamaBioengineering Program, Biological and Environmental Sciences and Engineering Division, King Abdullah University of Science and Technology (KAUST), 23955-6900 Thuwal, Saudi Arabia.ORCID 0000-0001-7742-1282

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Laser-scribed graphene electrodes (LSGEs) are promising platforms for the development of electrochemical biosensors for point-of-care settings and continuous monitoring and wearable applications. However, the frequent occurrence of biofouling drastically reduces the sensitivity and selectivity of these devices, hampering their sensing performance. Herein, we describe a versatile, low-impedance, and robust antibiofouling interface based on sulfobetaine-zwitterionic moieties. The interface induces the formation of a hydration layer and exerts electrostatic repulsion, protecting the electrode surface from the nonspecific adsorption of various biofouling agents. We demonstrate through electrochemical and microscopy techniques that the modified electrode exhibits outstanding antifouling properties, preserving more than 90% of the original signal after 24 h of exposure to bovine serum albumin protein, HeLa cells, and

Indexed as

BiofoulingBiosensing TechniquesGraphiteElectric ImpedanceElectrochemical TechniquesElectrodesHeLa CellsHumansLasersPorositySerum Albumin, BovineGraphiteSerum Albumin, Bovineantibiofoulingbiosensorslaser-scribed graphenepoint-of-care diagnosticszwitterionic

Identifiers

PMID38231564
PMCPMC10835659

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.