Evidence map›Paper›PMID 38231447›Full record

ArticleActa neurochirurgica2024

Stereotactic radiosurgery for brain arteriovenous malformations in patients with hereditary hemorrhagic telangiectasia.

Eduardo Orrego González, Sean Runge, Georgios Mantziaris, Natasha Ironside, Jason P Sheehan

Open access · hybridAbstract read
In one paragraph

Article in Acta neurochirurgica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Eduardo Orrego GonzálezDepartment of Neurological Surgery, University of Virginia Health System, Charlottesville, VA, 22908, USA.
Sean RungeDepartment of Neurological Surgery, University of Virginia Health System, Charlottesville, VA, 22908, USA.
Georgios MantziarisDepartment of Neurological Surgery, University of Virginia Health System, Charlottesville, VA, 22908, USA.
Natasha IronsideDepartment of Neurological Surgery, University of Virginia Health System, Charlottesville, VA, 22908, USA.
Jason P SheehanDepartment of Neurological Surgery, University of Virginia Health System, Charlottesville, VA, 22908, USA. Jps2f@uvahealth.org.
Neurological Surgery · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveBrain arteriovenous malformations (AVMs) in patients with hereditary hemorrhagic telangiectasia (HHT) present different characteristics from sporadic AVMs, and they have lower initial bleeding rates. Conservative management is usually preferred for the treatment of these lesions. In this case study, we present the largest series of HHT patients treated with stereotactic radiosurgery to date.

methodsWe identified eight patients with HHT and 14 AVMs. We retrospectively collected clinical, radiographic, and treatment characteristics of the patients and each AVM.

resultsMost patients in our sample presented with small AVMs. The median volume of these AVMs was 0.22 cm

conclusionsPatients with HHT who present with multiple brain AVMs are generally well served by SRS. Obliteration can be achieved in the majority of HHT patients and with a low complication rate. In the current study, initial hemorrhage rates prior to SRS were noticeable which supports the decision to treat these AVMs. Future studies are needed to better address the role of SRS for HHT patients harboring ruptured and unruptured AVMs.

Indexed as

Arteriovenous MalformationsRadiosurgeryTelangiectasia, Hereditary HemorrhagicBrainHumansRetrospective StudiesHereditary hemorrhagicIntracranial arteriovenous malformationIntracranial hemorrhagesRadiosurgeryTelangiectasia

Identifiers

PMID38231447
PMCPMC10794397
OpenAlexW4390951726

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.