Evidence map›Paper›PMID 38231416›Full record

ArticleNaunyn-Schmiedeberg's archives of pharmacology2024

Analysis of biosimilars consumption in an Italian Local Health Authority.

Francesco Ferrara, Maurizio Capuozzo, Roberto Langella, Ugo Trama, Eduardo Nava, Alessandro Ottaiano, Andrea Zovi

Abstract read
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In one paragraph

Article in Naunyn-Schmiedeberg's archives of pharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Francesco FerraraPharmacy Department, Asl Napoli 3 Sud, Dell'amicizia Street 22, 80035, Naples, Nola, Italy. ferrarafr@libero.it.ORCID http://orcid.org/0000-0001-9298-6783
Maurizio CapuozzoPharmaceutical Department, Asl Napoli 3 Sud, Marittima Street 3, 80056, Ercolano, Naples, Italy.ORCID http://orcid.org/0000-0001-9488-6057
Roberto LangellaItalian Society of Hospital Pharmacy (SIFO), SIFO Secretariat of the Lombardy Region, Via Carlo Farini, 81, 20159, Milan, Italy.
Ugo TramaGeneral Direction for Health Protection and Coordination of the Campania Regional Health System, Naples, Italy.
Eduardo NavaPharmacy Department, Asl Napoli 3 Sud, Dell'amicizia Street 22, 80035, Naples, Nola, Italy.
Alessandro OttaianoIstituto Nazionale Tumori Di Napoli, IRCCS "G. Pascale," Via M. Semmola, 80131, Naples, Italy.
Andrea ZoviMinistry of Health, Viale Giorgio Ribotta 5, 00144, Rome, Italy.ORCID http://orcid.org/0000-0002-6528-2171

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biosimilar drugs offer an opportunity for all global healthcare systems because they provide significant cost savings while ensuring equal efficacy and safety in the treatment of chronic diseases. These savings can be allocated to support ongoing innovation. An analysis of the usage of major biosimilar drugs across various therapeutic areas has been conducted within an Italian healthcare company serving a population of over one million. Data on consumption, expenditure, and the number of treated patients has been extracted from the company's databases. Finally, a comparison with the year 2021 has been performed to determine if biosimilar drug usage increased in 2022. In 2022, the data reveals that a substantial portion of the analysed active ingredients are being used as biosimilar drugs, except in a few residual cases. However, among the most consumed drugs, resistance still exists in the case of Adalimumab and Etanercept, for which expenditure on originator drugs exceeds 2 million euros. The 2022-2021 comparison highlights the increasing use of biosimilar drugs. This data is encouraging and suggests that in the coming months, we may achieve total utilization, which would be to the benefit of the National Healthcare System (NHS) and the citizens who can rely on an efficient and sustainable healthcare policy that is continually improving.

Indexed as

Biosimilar PharmaceuticalsDrug CostsDrug UtilizationHumansItalyBiosimilar PharmaceuticalsBiological drugsBiosimilarsBiotechnologicalCost-containment strategiesPharmaceuticalsProteinsSustainabilityTherapeutic

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.