Evidence map›Paper›PMID 38231260›Full record

ReviewSkeletal radiology2024

Recent advances in molecular profiling of bone and soft tissue tumors.

D Baumhoer, J Hench, F Amary

Abstract readReview
In one paragraph

Review in Skeletal radiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Diagnosis and Management of Soft-Tissue Sarcomas: Current Insights.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2026
    Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

D BaumhoerBone Tumor and DOESAK Reference Center, Institute of Medical Genetics and Pathology, University Hospital and University of Basel, Schoenbeinstrasse 40, 4031, Basel, Switzerland. daniel.baumhoer@usb.ch.ORCID http://orcid.org/0000-0002-2137-7507
J HenchInstitute of Medical Genetics and Pathology, University Hospital and University of Basel, Basel, Switzerland.
F AmaryDepartment of Histopathology, Royal National Orthopaedic Hospital, Greater London, Stanmore, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The molecular characterization of soft tissue and bone tumors is a rapidly evolving field that has changed the perspective of how these tumors are diagnosed today. Morphology and clinico-radiological context still represent the cornerstone of diagnostic considerations but are increasingly complemented by molecular data that aid in objectifying and confirming the classification. The spectrum of analyses comprises mutation or gene fusion specific immunohistochemical antibodies, fluorescence in situ hybridization, DNA and RNA sequencing as well as CpG methylation profiling. This article provides an overview of which tools are presently available to characterize bone and soft tissue neoplasms molecularly, what limitations should be considered, and what conclusions can be drawn from the individual findings.

Indexed as

Bone NeoplasmsSoft Tissue NeoplasmsBiomarkers, TumorDNA MethylationGene Expression ProfilingHumansImmunohistochemistryMutationBiomarkers, TumorBone tumorsDNA sequencingMethylome profilingRNA sequencingSoft tissue tumors

Identifiers

PMID38231260
PMCPMC11303483

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.