Evidence map›Paper›PMID 38231137›Full record

ArticleInorganic chemistry2024

Class Ib Ribonucleotide Reductases: Activation of a Peroxido-Mn

Lorna Doyle, Adriana Magherusan, Shuangning Xu, Kayleigh Murphy, Erik R Farquhar, Florian Molton, Carole Duboc, Lawrence Que, Aidan R McDonald

Open access · hybridAbstract read
In one paragraph

Article in Inorganic chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Lorna DoyleSchool of Chemistry, Trinity College Dublin, The University of Dublin, College Green, Dublin 2, Ireland.
Adriana MagherusanSchool of Chemistry, Trinity College Dublin, The University of Dublin, College Green, Dublin 2, Ireland.
Shuangning XuDepartment of Chemistry and Centre for Metals in Biocatalysis, University of Minnesota, 207 Pleasant Street SE, Minneapolis, Minnesota 55455, United States.ORCID 0000-0002-3391-3952
Kayleigh MurphySchool of Chemistry, Trinity College Dublin, The University of Dublin, College Green, Dublin 2, Ireland.
Erik R FarquharCase Western Reserve University Center for Synchrotron Biosciences, National Synchrotron Light Source II, Brookhaven National Laboratory Upton, New York 11973, United States.ORCID 0000-0002-6419-038X
Florian MoltonCNRS UMR 5250, DCM, Univ. Grenoble Alpes, Grenoble F-38000, France.
Carole DubocCNRS UMR 5250, DCM, Univ. Grenoble Alpes, Grenoble F-38000, France.ORCID 0000-0002-9415-198X
Lawrence QueDepartment of Chemistry and Centre for Metals in Biocatalysis, University of Minnesota, 207 Pleasant Street SE, Minneapolis, Minnesota 55455, United States.ORCID 0000-0002-0989-2813
Aidan R McDonaldSchool of Chemistry, Trinity College Dublin, The University of Dublin, College Green, Dublin 2, Ireland.ORCID 0000-0002-8930-3256
Trinity College Dublin · IECentre National de la Recherche Scientifique · FRUniversity of Minnesota · USBrookhaven National Laboratory · US

Funding

O-O Bond Activation (and Formation) at Bimetallic Enzyme Active SitesR35GM131721 · NIGMS · UNIVERSITY OF MINNESOTA · PI QUE, LAWRENCE · 2019 to 2023
$1.7M
NIGMS NIH HHS R35 GM131721
6 · The paper itself

Abstract

In the postulated catalytic cycle of class Ib Mn

Indexed as

OxidantsRibonucleotide ReductasesManganeseOxidation-ReductionSuperoxidesTyrosineManganeseOxidantsRibonucleotide ReductasesSuperoxidesTyrosine

Identifiers

PMID38231137
PMCPMC10828993
OpenAlexW4390940247

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.