Evidence map›Paper›PMID 38230956›Full record

ArticleMicrobiology spectrum2024

Mass spectrometry and split luciferase complementation assays reveal the MecA protein interactome of

Hua Qin, David Anderson, Zhengzhong Zou, Dustin Higashi, Christina Borland, Jens Kreth, Justin Merritt

Abstract read
In one paragraph

Article in Microbiology spectrum, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. MecA inmSphere · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hua QinDivision of Biomaterial and Biomedical Sciences, Oregon Health & Science University, Portland, Oregon, USA.ORCID 0000-0003-4832-9895
David AndersonDivision of Biomaterial and Biomedical Sciences, Oregon Health & Science University, Portland, Oregon, USA.
Zhengzhong ZouDivision of Biomaterial and Biomedical Sciences, Oregon Health & Science University, Portland, Oregon, USA.
Dustin HigashiDivision of Biomaterial and Biomedical Sciences, Oregon Health & Science University, Portland, Oregon, USA.
Christina BorlandDivision of Biomaterial and Biomedical Sciences, Oregon Health & Science University, Portland, Oregon, USA.
Jens KrethDivision of Biomaterial and Biomedical Sciences, Oregon Health & Science University, Portland, Oregon, USA.ORCID 0000-0002-8599-8310
Justin MerrittDivision of Biomaterial and Biomedical Sciences, Oregon Health & Science University, Portland, Oregon, USA.ORCID 0000-0002-3464-0490

Funding

Advancing studies of polymicrobial diseases via streptococcal geneticsR35DE028252 · NIDCR · OREGON HEALTH & SCIENCE UNIVERSITY · PI MERRITT, JUSTIN · 2018 to 2025
$7.8M
Pyruvate oxidase: a molecular determinant of commensalism among the oral microbiomeR01DE029492 · NIDCR · OREGON HEALTH & SCIENCE UNIVERSITY · PI KRETH, JENS · 2020 to 2024
$2.5M
Pyruvate oxidase determines ecological fitness of oral streptococciR01DE021726 · NIDCR · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI KRETH, JENS · 2014 to 2018
$1.9M
Pyruvate oxidase determines ecological fitness of oral streptococciR56DE021726 · NIDCR · OREGON HEALTH & SCIENCE UNIVERSITY · PI KRETH, JENS · 2018 to 2018
$545k
Streptococcal secretion of pyruvate - a novel antioxidant strategy in the oral biofilmR21DE029612 · NIDCR · OREGON HEALTH & SCIENCE UNIVERSITY · PI KRETH, JENS · 2020 to 2021
$424k
NIDCR NIH HHS R01 DE021726NIDCR NIH HHS R01 DE029492NIDCR NIH HHS R21 DE029612NIDCR NIH HHS R35 DE028252NIDCR NIH HHS R56 DE021726
6 · The paper itself

Abstract

MecA is a highly conserved adaptor protein encoded by prokaryotes from the

Indexed as

Bacterial ProteinsStreptococcus mutansLuciferasesMass SpectrometryProteolysisBacterial ProteinsLuciferasesmass spectrometryMecA interactomeprotein binding affinitysplit luciferase complementation assaysStreptococcus mutans

Identifiers

PMID38230956
PMCPMC10845952

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.