Iridium-catalysed hydroamination of internal homoallylic amines.

An T Ho, Evan P Vanable, Chelsea San Miguel, Kami L Hull

Abstract read

In one paragraph

Article in Chemical communications (Cambridge, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

An T HoDepartment of Chemistry, University of Texas at Austin, 100 East 24th Street, Austin, TX 78741, USA. kamihull@utexas.edu.

Evan P VanableDepartment of Chemistry, University of Illinois at Urbana-Champaign, 600 South Mathews Avenue, Urbana, Illinois 61801, USA.

Chelsea San MiguelDepartment of Chemistry, University of Texas at Austin, 100 East 24th Street, Austin, TX 78741, USA. kamihull@utexas.edu.

Kami L HullDepartment of Chemistry, University of Texas at Austin, 100 East 24th Street, Austin, TX 78741, USA. kamihull@utexas.edu.ORCID http://orcid.org/0000-0003-3102-2686

Funding

Transition Metal-Catalyzed Alkene FunctionalizationR35GM125029 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI Kami Lee Hull · 2017 to 2026

$2.7M

NIGMS NIH HHS R35 GM125029

6 · The paper itself

Abstract

An Ir-catalysed regioselective hydroamination of internal homoallylic amines is reported. Both cyclic and acyclic internal olefins undergo directed hydroamination reactions with both aromatic and cyclic aliphatic amines to afford a variety of 1,4-diamines in fair to excellent yields. Diastereoselectivity and mechanistic investigations support that for cyclic substrates the reactions are proceeding

Identifiers

PMID38230687

DOI10.1039/d3cc05594a

PMCPMC10846566

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.