Evidence map›Paper›PMID 38230398›Full record

ArticleJournal of contemporary brachytherapy2023

Clinical outcomes of single application multi-fractionated CT-guided interstitial high-dose-rate brachytherapy for locally advanced cervical cancer: A multi-institution initial experience.

Eugene T Yap, Mark P Dumago, Carl Jay Jainar, Maureen Bojador, Stellar Marie Cabrera, Gil S Gonzalez, Jocelyn Z Mariano, Aida Bautista, Jhustine Mababangloob, Janell Marie Genson and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of contemporary brachytherapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Eugene T YapDepartment of Radiation Oncology, Benavides Cancer Institute, University of Santo Tomas Hospital, Philippines.
Mark P DumagoDepartment of Radiation Oncology, Benavides Cancer Institute, University of Santo Tomas Hospital, Philippines.
Carl Jay JainarDepartment of Radiation Oncology, Benavides Cancer Institute, University of Santo Tomas Hospital, Philippines.
Maureen BojadorDepartment of Radiation Oncology, Benavides Cancer Institute, University of Santo Tomas Hospital, Philippines.
Stellar Marie CabreraDepartment of Radiation Oncology, Benavides Cancer Institute, University of Santo Tomas Hospital, Philippines.
Gil S GonzalezSection of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Santo Tomas Hospital, Philippines.
Jocelyn Z MarianoSection of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Santo Tomas Hospital, Philippines.
Aida BautistaSection of Gynecologic Oncology, Department of Obstetrics and Gynecology, Manila Doctors Hospital, Philippines.
Jhustine MababangloobDepartment of Radiation Oncology, Manila Doctors Hospital, Philippines.
Janell Marie GensonDepartment of Radiation Oncology, Manila Doctors Hospital, Philippines.
Teresa Sy OrtinDepartment of Radiation Oncology, Benavides Cancer Institute, University of Santo Tomas Hospital, Philippines.
Warren R BacorroDepartment of Radiation Oncology, Benavides Cancer Institute, University of Santo Tomas Hospital, Philippines.
University of Santo Tomas Hospital · PHGynecologic Oncology Group · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: The aim of the study was to evaluate the safety and clinical outcomes of single application multi-fractionated computed tomography (CT)-guided interstitial high-dose-rate brachytherapy given in four fractions in locally advanced cervical cancer. Material and methods: Patients with locally advanced cervical cancer stage IIB-IVA treated definitively with external radiation ± weekly cisplatin, followed by single application multi-fractionated CT-guided interstitial high-dose-rate brachytherapy in four fractions were included. Dosimetry data, clinical response, and toxicity records were reviewed. Results: Between January 2018 and December 2022, twenty-two patients were included. Clinical stage distribution was as follows: IIB - 13.6%, IIIB - 27.3%, IIIC - 22.7%, and IVA - 36.4%. Mean high-risk clinical target volume (HR-CTV) was 66.19 ±32.69 cm Conclusions: Initial results suggest that single application multi-fractionated CT-guided interstitial brachytherapy given in four fractions in locally advanced cervical cancer seems to be feasible and safe, but additional evidence is needed to generate more validated conclusions.

Indexed as

cervical cancerCT-guidedhigh-dose-rateinterstitial brachytherapysingle application

Identifiers

PMID38230398
PMCPMC10789154
OpenAlexW4390680375

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.