Evidence map›Paper›PMID 38230352›Full record

ArticleJAC-antimicrobial resistance2024

Comparative molecular profiling of multidrug-resistant

Nitasha D Menon, Priyanka Somanath, Jennifer Jossart, Gayathri Vijayakumar, Kavya Shetty, Manasi Baswe, Meghna Chatterjee, Malavika B Hari, Samitha Nair, V Anil Kumar and 4 more

Open access · goldAbstract read
In one paragraph

Article in JAC-antimicrobial resistance, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Antibiotic Choice for Carbapenem-resistantIndian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2026
    Article
  3. Emergence of outbreak-driving high-riskMicrobial genomics · 2026
    Article
  4. Review
  5. Differences in antimicrobial resistance between exoU and exoS isolates of Pseudomonas aeruginosa.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 2 countries.

Nitasha D MenonSchool of Biotechnology, Amrita Vishwa Vidyapeetham, Amritapuri, Kerala, India.ORCID https://orcid.org/0000-0002-1277-7648
Priyanka SomanathSchool of Biotechnology, Amrita Vishwa Vidyapeetham, Amritapuri, Kerala, India.ORCID https://orcid.org/0009-0003-3074-6161
Jennifer JossartDepartment of Molecular Diagnostics and Experimental Therapeutics, City of Hope, Duarte, CA, USA.
Gayathri VijayakumarSchool of Biotechnology, Amrita Vishwa Vidyapeetham, Amritapuri, Kerala, India.
Kavya ShettySchool of Biotechnology, Amrita Vishwa Vidyapeetham, Amritapuri, Kerala, India.
Manasi BasweSchool of Biotechnology, Amrita Vishwa Vidyapeetham, Amritapuri, Kerala, India.
Meghna ChatterjeeSchool of Biotechnology, Amrita Vishwa Vidyapeetham, Amritapuri, Kerala, India.
Malavika B HariSchool of Biotechnology, Amrita Vishwa Vidyapeetham, Amritapuri, Kerala, India.
Samitha NairDepartment of Microbiology, DDRC SRL Diagnostic Private Limited, Trivandrum, Kerala, India.
V Anil KumarDepartment of Microbiology, Amrita Institute of Medical Sciences, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India.ORCID https://orcid.org/0000-0002-7240-4691
Bipin G NairSchool of Biotechnology, Amrita Vishwa Vidyapeetham, Amritapuri, Kerala, India.
Victor NizetDepartment of Pharmacology, University of California, San Diego, La Jolla, CA, USA.
J Jefferson P PerryDepartment of Molecular Diagnostics and Experimental Therapeutics, City of Hope, Duarte, CA, USA.
Geetha B KumarSchool of Biotechnology, Amrita Vishwa Vidyapeetham, Amritapuri, Kerala, India.ORCID https://orcid.org/0000-0002-4584-6929
Tata Institute for Genetics and Society · INCity of Hope · USAmrita Institute of Medical Sciences and Research Centre · INUniversity of California San Diego · USVRR Diagnostic Services (India) · IN

Funding

DNA Damage Response and Oncogenic SignalingT32CA186895 · NCI · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI BINGHUI SHEN, Jeremy Michael Stark · 2016 to 2026
$2.1M
Surprising Efficacy of Discounted Antibiotics vs. MDR Gram-Negative Pathogens Occurring Through Innate Immune SensitizationR01AI145310 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI KUMARASWAMY, MONIKA, NIZET, VICTOR · 2020 to 2023
$1.9M
NCI NIH HHS T32 CA186895NIAID NIH HHS R01 AI145310
6 · The paper itself

Abstract

Objectives: We sought to analyse the antibiotic susceptibility profiles and molecular epidemiology of MDR clinical Methods: We established a comprehensive clinical strain library consisting of 58 isolates collected from patients across the South Indian state of Kerala from March 2017 to July 2019. The strains were subject to antibiotic susceptibility testing, modified carbapenem inactivation method assay for carbapenemase production, PCR sequencing, comparative sequence analysis and quantitative PCR of MDR determinants associated with antibiotic efflux pump systems, fluoroquinolone resistance and carbapenem resistance. We performed Results: Of our collection of South Indian Conclusions: This study provides insight into MDR mechanisms adopted by

Identifiers

PMID38230352
PMCPMC10789591
OpenAlexW4390894603

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.