Evidence map›Paper›PMID 38230266›Full record

ArticleObesity pillars2024

Once-weekly semaglutide administered after laparoscopic sleeve gastrectomy: Effects on body weight, glycemic control, and measured nutritional metrics in Japanese patients having both obesity and type 2 diabetes.

Rieko Kanai, Sachiho Kinoshita, Izumi Kanbe, Mariko Sameda, Shuhei Yamaoka, Osamu Horikawa, Yasuhiro Watanabe, Ichiro Tatsuno, Kohji Shirai, Takashi Oshiro and 1 more

Open access · diamondAbstract read
In one paragraph

Article in Obesity pillars, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 4 pooled it
8.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 4 syntheses or guidelines pooled it, 14 citations in OpenAlex.

  1. A Systematic Review and Meta-Analysis of Semaglutide Effects on Adipose Tissue and Emerging Effects on Brain and Cognition.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Rieko KanaiDepartment of Medical Nutrition, Toho University Sakura Medical Center, Sakura, Japan.
Sachiho KinoshitaDepartment of Medical Nutrition, Toho University Sakura Medical Center, Sakura, Japan.
Izumi KanbeDepartment of Medical Nutrition, Toho University Sakura Medical Center, Sakura, Japan.
Mariko SamedaDepartment of Medical Nutrition, Toho University Sakura Medical Center, Sakura, Japan.
Shuhei YamaokaCenter of Diabetes, Endocrine and Metabolism, Toho University Sakura Medical Center, Sakura, Japan.
Osamu HorikawaCenter of Diabetes, Endocrine and Metabolism, Toho University Sakura Medical Center, Sakura, Japan.
Yasuhiro WatanabeCenter of Diabetes, Endocrine and Metabolism, Toho University Sakura Medical Center, Sakura, Japan.
Ichiro TatsunoCenter of Diabetes, Endocrine and Metabolism, Toho University Sakura Medical Center, Sakura, Japan.
Kohji ShiraiCenter of Diabetes, Endocrine and Metabolism, Toho University Sakura Medical Center, Sakura, Japan.
Takashi OshiroDepartment of Surgery, Toho University Sakura Medical Center, Sakura, Japan.
Atsuhito SaikiDepartment of Medical Nutrition, Toho University Sakura Medical Center, Sakura, Japan.
Toho University · JPChiba Prefectural University of Health Sciences · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Glucagon-like peptide (GLP)-1 analogue may be useful for controlling weight recurrence and diabetes relapse after bariatric surgery, but may also adversely affect the measured nutritional metrics. This study aimed to investigate the effect of treatment with once-weekly semaglutide after laparoscopic sleeve gastrectomy (LSG) in patients with type 2 diabetes (T2D). We also examined the effects of combined use with a low-energy, high-protein formula diet (FD). Methods: This study was a single-center retrospective database analysis. We enrolled 29 Japanese patients with T2D who underwent LSG, and more than 12 months later received semaglutide. The patients were divided retrospectively into a FD group (=6) and a conventional diet (CD) group (n = 23). Results: BMI and HbA1c decreased significantly by 10.7 kg/m Conclusion: Semaglutide after LSG in patients with obesity and T2D resulted in additional weight reduction and improved glycemic control, but worsened measured nutritional metrics. Administration of a low-energy, high protein formula diet may ameliorate adverse nutritional effects of semaglutide in patients with T2D after LSG. (Ethics Committee of Toho University Sakura Medical Center approval number S18061).

Indexed as

Formula dietLaparoscopic sleeve gastrectomyOnce-weekly glucagon-like peptide 1 receptor agonistSemaglutideType 2 diabetes

Identifiers

PMID38230266
PMCPMC10789635
OpenAlexW4390572390

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.