Evidence map›Paper›PMID 38229914›Full record

ArticleCase reports in anesthesiology2024

Anesthetic Management and Neuromonitoring in a Patient with Very Long-Chain Acyl-Coenzyme A Dehydrogenase Deficiency Undergoing Scoliosis Surgery: A Case Report and Review of Literature.

Anna Tanaka, Tim Cai, Michael Platten, Luis E Tollinche, Samuel J DeJoy

Registry-linked trialOpen access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in anesthesiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03808077 (A Randomized Controlled Trial to Compare the Effectiveness of Deep vs. Moderate Neuromuscular Blockade in Reducing Postoperative Pain and Intra-Abdominal Insufflation Pressure During Minimally Invasive Robotic Prostatectomy), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 100% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03808077 phase2active not recruitingnot on this map

A Randomized Controlled Trial to Compare the Effectiveness of Deep vs. Moderate Neuromuscular Blockade in Reducing Postoperative Pain and Intra-Abdominal Insufflation Pressure During Minimally Invasive Robotic Prostatectomy

TypeinterventionalSponsorMemorial Sloan Kettering Cancer CenterRan2019 to 2027Enrolled139ConditionsProstate CancerArmsRocuronium 0.3mg/kg/hr, Rocuronium 1.5mg/kg/hr
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Anna TanakaCase Western Reserve University School of Medicine, Cleveland, OH, USA.ORCID https://orcid.org/0009-0006-7318-3356
Tim CaiDepartment of Anesthesiology, MetroHealth Medical Center of Case Western Reserve University School of Medicine, Cleveland, OH, USA.
Michael PlattenDepartment of Anesthesiology, MetroHealth Medical Center of Case Western Reserve University School of Medicine, Cleveland, OH, USA.ORCID https://orcid.org/0009-0005-7558-0454
Luis E TollincheDepartment of Anesthesiology, MetroHealth Medical Center of Case Western Reserve University School of Medicine, Cleveland, OH, USA.ORCID https://orcid.org/0000-0002-1283-7102
Samuel J DeJoyDepartment of Anesthesiology, MetroHealth Medical Center of Case Western Reserve University School of Medicine, Cleveland, OH, USA.ORCID https://orcid.org/0009-0008-1545-2903
MetroHealth Medical Center · USUniversity School · US

Funding

Clinical and Translational Science Collaborative of ClevelandUL1TR002548 · NCATS · CASE WESTERN RESERVE UNIVERSITY · PI MCCOMSEY, GRACE A · 2018 to 2022
$35.5M
NCATS NIH HHS UL1 TR002548
6 · The paper itself

Abstract

Patients with very long-chain acyl-CoA dehydrogenase deficiency (VLCADD) are prone to hypoglycemia and clinical decompensation when metabolic demands of the body are not met. We present a pediatric patient with VLCADD who underwent a posterior spinal fusion for scoliosis requiring intraoperative neurophysiology monitoring. Challenges included minimization of perioperative metabolic stressors and careful selection of anesthetic agents since propofol-based total intravenous anesthesia (TIVA) was contraindicated due to its high fatty acid content. This case is unique due to the sequential use of inhaled anesthetics after TIVA to allow for a rapid wakeup and immediate postoperative physical exam. Additionally, intraoperative neuromonitoring in the setting of VLCADD has not been reported in the literature. With communication among anesthesia, surgery, and neuromonitoring teams before and during the operation, the patient successfully underwent a major surgery without complications. This trial is registered with NCT03808077.

Identifiers

PMID38229914
PMCPMC10789510
OpenAlexW4390660698

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.