Evidence map›Paper›PMID 38229827›Full record

ArticleJournal of Taibah University Medical Sciences2024

Polymethylmethacrylate-hydroxyapatite antibacterial and antifungal activity against oral bacteria: An in vitro study.

Tania Saskianti, Karina K Wardhani, Naura Fadhila, Soegeng Wahluyo, Ardianti M Dewi, Alexander P Nugraha, Diah S Ernawati, Masami Kanawa

Abstract read
In one paragraph

Article in Journal of Taibah University Medical Sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tania SaskiantiDepartment of Pediatric Dentistry, Faculty of Dental Medicine, Universitas Airlangga, Indonesia.
Karina K WardhaniDepartment of Pediatric Dentistry, Faculty of Dental Medicine, Universitas Airlangga, Indonesia.
Naura FadhilaDepartment of Pediatric Dentistry, Faculty of Dental Medicine, Universitas Airlangga, Indonesia.
Soegeng WahluyoDepartment of Pediatric Dentistry, Faculty of Dental Medicine, Universitas Airlangga, Indonesia.
Ardianti M DewiDepartment of Pediatric Dentistry, Faculty of Dental Medicine, Universitas Airlangga, Indonesia.
Alexander P NugrahaDepartment of Orthodontics, Faculty of Dental Medicine, Universitas Airlangga, Indonesia.
Diah S ErnawatiDepartment of Oral Medicine, Faculty of Dental Medicine, Universitas Airlangga, Indonesia.
Masami KanawaDepartment of Natural Science Center for Basic Research and Development, Hiroshima University, Higashi-Hiroshima, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Reconstruction of alveolar bone defects resulting from aging, trauma, ablative surgery or pathology, remains a significant clinical challenge. The objective of this study was to investigate the antibacterial and antifungal activities of mixed polymethylmethacrylate-hydroxyapatite (PMMA-HA) against oral microorganisms. Our findings could provide valuable insights into the prospective application of PMMA-HA as a synthetic bone graft material to manage alveolar bone defects Methods: HA powder was obtained from the Center for Ceramics in Indonesia and PMMA granules were obtained from HiMedia Laboratories; these were prepared in 20:80, 30:70, and 40:60 ratios. The antibacterial diffusion method was then performed against Results: A PMMA-HA scaffold with a 20:80 ratio demonstrated the highest antibacterial activity against Conclusion: PMMA-HA scaffolds have significant activity against bacteria, but not against fungi.

Indexed as

Alveolar bone defectAntibacterialAntifungalHydroxyapatiteMedicinePolymethylmethacrylate

Identifiers

PMID38229827
PMCPMC10790095

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.