Evidence map›Paper›PMID 38229748›Full record

ArticleACS medicinal chemistry letters2024

Structure-Based Design and Evaluation of Reversible KRAS G13D Inhibitors.

Christian Nilewski, Sharada Labadie, Binqing Wei, Sushant Malhotra, Steven Do, Lewis Gazzard, Li Liu, Cheng Shao, Jeremy Murray, Yevgeniy Izrayelit and 6 more

Open access · greenAbstract read
In one paragraph

Article in ACS medicinal chemistry letters, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Christian NilewskiGenentech Inc., 1 DNA Way, South San Francisco, California 94080, United States.ORCID https://orcid.org/0000-0002-8030-9571
Sharada LabadieGenentech Inc., 1 DNA Way, South San Francisco, California 94080, United States.
Binqing WeiGenentech Inc., 1 DNA Way, South San Francisco, California 94080, United States.ORCID https://orcid.org/0000-0002-3654-3459
Sushant MalhotraGenentech Inc., 1 DNA Way, South San Francisco, California 94080, United States.
Steven DoGenentech Inc., 1 DNA Way, South San Francisco, California 94080, United States.
Lewis GazzardGenentech Inc., 1 DNA Way, South San Francisco, California 94080, United States.
Li LiuPharmaron-Beijing Co. Ltd., 6 Taihe Road, BDA, Beijing 100176, P. R. China.
Cheng ShaoPharmaron-Beijing Co. Ltd., 6 Taihe Road, BDA, Beijing 100176, P. R. China.
Jeremy MurrayGenentech Inc., 1 DNA Way, South San Francisco, California 94080, United States.
Yevgeniy IzrayelitGenentech Inc., 1 DNA Way, South San Francisco, California 94080, United States.
Amy GustafsonGenentech Inc., 1 DNA Way, South San Francisco, California 94080, United States.
Nicholas F EndresGenentech Inc., 1 DNA Way, South San Francisco, California 94080, United States.
Fang MaGenentech Inc., 1 DNA Way, South San Francisco, California 94080, United States.
Xin YeGenentech Inc., 1 DNA Way, South San Francisco, California 94080, United States.
Jun ZouGenentech Inc., 1 DNA Way, South San Francisco, California 94080, United States.
Marie EvangelistaGenentech Inc., 1 DNA Way, South San Francisco, California 94080, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oncogenic

Identifiers

PMID38229748
PMCPMC10788945
OpenAlexW4389384338

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.