Evidence map›Paper›PMID 38229473›Full record

ArticleJournal of intellectual disability research : JIDR2024

Remote assessment of the Penn computerised neurocognitive battery in individuals with 22q11.2 deletion syndrome.

L K White, N Hillman, K Ruparel, T M Moore, R S Gallagher, E J McClellan, D R Roalf, J C Scott, M E Calkins, D E McGinn and 8 more

Abstract read
In one paragraph

Article in Journal of intellectual disability research : JIDR, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

L K WhiteLifespan Brain Institute (LiBI) of, Children's Hospital of Philadelphia and Penn Medicine, Philadelphia, PA, USA.ORCID 0000-0002-6394-4768
N HillmanDepartment of Psychiatry, Perelman School of Medicine of the University of Pennsylvania, Philadelphia, PA, USA.
K RuparelLifespan Brain Institute (LiBI) of, Children's Hospital of Philadelphia and Penn Medicine, Philadelphia, PA, USA.
T M MooreDepartment of Psychiatry, Perelman School of Medicine of the University of Pennsylvania, Philadelphia, PA, USA.
R S GallagherLifespan Brain Institute (LiBI) of, Children's Hospital of Philadelphia and Penn Medicine, Philadelphia, PA, USA.
E J McClellanLifespan Brain Institute (LiBI) of, Children's Hospital of Philadelphia and Penn Medicine, Philadelphia, PA, USA.
D R RoalfDepartment of Psychiatry, Perelman School of Medicine of the University of Pennsylvania, Philadelphia, PA, USA.
J C ScottDepartment of Psychiatry, Perelman School of Medicine of the University of Pennsylvania, Philadelphia, PA, USA.
M E CalkinsLifespan Brain Institute (LiBI) of, Children's Hospital of Philadelphia and Penn Medicine, Philadelphia, PA, USA.
D E McGinnDepartment of Psychiatry, Perelman School of Medicine of the University of Pennsylvania, Philadelphia, PA, USA.
V Giunta22q and You Center, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
O Tran22q and You Center, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
T B Crowley22q and You Center, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
E H ZackaiDepartment of Psychiatry, Perelman School of Medicine of the University of Pennsylvania, Philadelphia, PA, USA.
B S EmanuelDepartment of Psychiatry, Perelman School of Medicine of the University of Pennsylvania, Philadelphia, PA, USA.
D M McDonald-McGinnDepartment of Psychiatry, Perelman School of Medicine of the University of Pennsylvania, Philadelphia, PA, USA.
R E GurLifespan Brain Institute (LiBI) of, Children's Hospital of Philadelphia and Penn Medicine, Philadelphia, PA, USA.
R C GurLifespan Brain Institute (LiBI) of, Children's Hospital of Philadelphia and Penn Medicine, Philadelphia, PA, USA.

Funding

Ultra-high field GluCEST MRI and MRS in youth at risk for psychosisR01MH120174 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI ROALF, DAVID R · 2020 to 2024
$3.8M
Evolution of Psychosis in Youth: Multimodal Risk and Resilience MarkersR01MH119219 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI GUR, RAQUEL E, GUR, RUBEN C. · 2019 to 2023
$3.8M
Olfactory and facial markers of developmental risk for psychosis in 22q11 deletion syndromeR01MH119185 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI ROALF, DAVID R · 2019 to 2024
$3.5M
1/9: Dissecting the effects of genomic variants on nenriched for neuropsychiatric disorderseurobehavioral dimensions in CNVs U01MH119738 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI GUR, RAQUEL E · 2019 to 2023
$3.2M
Creating an adaptive screening tool for detecting neurocognitive deficits and psychopathology across the lifespanR01MH117014 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI GUR, RUBEN C. · 2019 to 2022
$2.9M
2/9: Dissecting the effects of genomic variants on neurobehavioral dimensions in CNVs enriched for neuropsychiatric disorders.U01MH119737 · NIMH · CHILDREN'S HOSP OF PHILADELPHIA · PI MCDONALD-MCGINN, DONNA MARIE · 2019 to 2023
$2.4M
NIMH NIH HHS MH117014NIMH NIH HHS MH119185NIMH NIH HHS MH119219NIMH NIH HHS MH119737NIMH NIH HHS MH119738NIMH NIH HHS MH120174NIMH NIH HHS R01 MH117014NIMH NIH HHS R01 MH119185NIMH NIH HHS R01 MH119219NIMH NIH HHS U01 MH119738
6 · The paper itself

Abstract

backgroundNeurocognitive functioning is an integral phenotype of 22q11.2 deletion syndrome relating to severity of psychopathology and outcomes. A neurocognitive battery that could be administered remotely to assess multiple cognitive domains would be especially beneficial to research on rare genetic variants, where in-person assessment can be unavailable or burdensome. The current study compares in-person and remote assessments of the Penn computerised neurocognitive battery (CNB).

methodsParticipants (mean age = 17.82, SD = 6.94 years; 48% female) completed the CNB either in-person at a laboratory (n = 222) or remotely (n = 162).

resultsResults show that accuracy of CNB performance was equivalent across the two testing locations, while slight differences in speed were detected in 3 of the 11 tasks.

conclusionsThese findings suggest that the CNB can be used in remote settings to assess multiple neurocognitive domains.

Indexed as

DiGeorge SyndromeAdolescentCognitionFemaleHumansMaleNeuropsychological TestsPhenotypePsychopathology22q11.2 deletion syndromecognitive assessmentsneurocognitionremote assessments

Identifiers

PMID38229473
PMCPMC13107926

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.