Evidence map›Paper›PMID 38229436›Full record

ArticleAnnals of geriatric medicine and research2024

Polypharmacy, Potentially Inappropriate Medications, and Dysphagia in Older Inpatients: A Multi-Center Cohort Study.

Shintaro Togashi, Hironori Ohinata, Taiji Noguchi, Hidetaka Wakabayashi, Mariko Nakamichi, Akio Shimizu, Shinta Nishioka, Ryo Momosaki

Open access · diamondAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of geriatric medicine and research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
3.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 1 country.

Shintaro TogashiCenter for Outcomes Research and Economic Evaluation for Health, National Institute of Public Health, Wako-shi, Japan.
Hironori OhinataFaculty of Health Sciences, Hokkaido University, Sapporo, Japan.
Taiji NoguchiDepartment of Social Science, Center for Gerontology and Social Science, Research Institute, National Center for Geriatrics and Gerontology, Obu, Japan.
Hidetaka WakabayashiDepartment of Rehabilitation Medicine, Tokyo Women's Medical University Hospital, Shinjuku, Japan.
Mariko NakamichiDepartment of Pharmacy, Haradoi Hospital, Fukuoka, Japan.
Akio ShimizuDepartment of Food and Health, Faculty of Health and Human Development, The University of Nagano, Nagano, Japan.
Shinta NishiokaDepartment of Clinical Nutrition and Food Service, Nagasaki Rehabilitation Hospital, Nagasaki, Japan.
Ryo MomosakiDepartment of Rehabilitation Medicine, Mie University Graduate School of Medicine, Tsu, Japan.
Haradoi Hospital · JPJapan Society for the Promotion of Science · JPMie University · JPNagano University of Health and Medicine · JPNational Institute of Public Health · JPSapporo University · JPTokyo Women's Medical University Hospital · JP

Funding

JSPS-KAKENHI 19H03979
6 · The paper itself

Abstract

backgroundAlthough the relationship between medication status, symptomatology, and outcomes has been evaluated, data on the prevalence of polypharmacy and potentially inappropriate medications (PIMs) and the association of polypharmacy and PIMs with swallowing function during follow-up are limited among hospitalized patients aged ≥65 years with dysphagia.

methodsIn this 19-center cohort study, we registered 467 inpatients aged ≥65 years and evaluated those with the Food Intake LEVEL Scale (FILS) scores ≤8 between November 2019 and March 2021. Polypharmacy was defined as prescribing ≥5 medications and PIMs were identified based on the 2023 Updated Beers Criteria. We applied a generalized linear regression model to examine the association of polypharmacy and PIMs with FILS score at discharge.

resultsWe analyzed 399 participants (median age, 83.0 years; males, 49.8%). The median follow-up was 51.0 days (interquartile range, 22.0-84.0 days). Polypharmacy and PIMs were present in 67.7% of and 56.1% of patients, respectively. After adjusting for covariates, neither polypharmacy (β = 0.05; 95% confidence interval [CI], -0.04-0.13, p=0.30) nor non-steroidal anti-inflammatory medications (β = 0.09; 95% CI, -0.02-0.19; p=0.10) were significantly associated with FILS score at discharge.

conclusionThe results of this study indicated a high proportion of polypharmacy and PIMs among inpatients aged ≥65 years with dysphagia. Although these prescribed conditions were not significantly associated with swallowing function at discharge, our findings suggest the importance of regularly reviewing medications to ensure the appropriateness of prescriptions when managing older inpatients.

Indexed as

Deglutition DisordersPolypharmacyPotentially Inappropriate Medication ListAgedAged, 80 and overCohort StudiesFemaleHospitalizationHumansInappropriate PrescribingInpatientsMaleDeglutition disordersGeriatricsPolypharmacyPotentially inappropriate medication list

Identifiers

PMID38229436
PMCPMC10982443
OpenAlexW4390952250

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.