Evidence map›Paper›PMID 38229301›Full record

ArticleApplied microbiology and biotechnology2024

Characterization of a novel aspartic protease from Trichoderma asperellum for the preparation of duck blood peptides.

Yibin Xue, Qiaojuan Yan, Xue Li, Zhengqiang Jiang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Applied microbiology and biotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Yibin Xue *Key Laboratory of Food Bioengineering (China National Light Industry), College of Food Science & Nutritional Engineering, China Agricultural University, Beijing, 100083, China.
Qiaojuan Yan *College of Engineering, China Agricultural University, Beijing, 100083, China.
Xue LiCollege of Engineering, China Agricultural University, Beijing, 100083, China.
Zhengqiang JiangKey Laboratory of Food Bioengineering (China National Light Industry), College of Food Science & Nutritional Engineering, China Agricultural University, Beijing, 100083, China. zhqjiang@cau.edu.cn.ORCID http://orcid.org/0000-0002-9573-2890
China Agricultural University · CNLuohe Medical College · CN

Funding

National Natural Science Foundation of China 32272913
6 · The paper itself

Abstract

A novel aspartic protease gene (TaproA1) from Trichoderma asperellum was successfully expressed in Komagataella phaffii (Pichia pastoris). TaproA1 showed 52.8% amino acid sequence identity with the aspartic protease PEP3 from Coccidioides posadasii C735. TaproA1 was efficiently produced in a 5 L fermenter with a protease activity of 4092 U/mL. It exhibited optimal reaction conditions at pH 3.0 and 50 °C and was stable within pH 3.0-6.0 and at temperatures up to 45 °C. The protease exhibited broad substrate specificity with high hydrolysis activity towards myoglobin and hemoglobin. Furthermore, duck blood proteins (hemoglobin and plasma protein) were hydrolyzed by TaproA1 to prepare bioactive peptides with high ACE inhibitory activity. The IC

Indexed as

Aspartic Acid ProteasesHypocrealesSaccharomycetalesTrichodermaAnimalsBlood ProteinsDucksFungal ProteinsHemoglobinsMyoglobinPeptidesAspartic Acid ProteasesBlood ProteinsFungal ProteinsHemoglobinsMyoglobinPeptidesAspartic proteaseBiochemical characterizationDuck blood peptidesKomagataella phaffiiTrichoderma asperellum

Identifiers

PMID38229301
PMCPMC10787677
OpenAlexW4390839171

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.