Evidence map›Paper›PMID 38229182›Full record

ArticlePorcine health management2024

Frequency of PCV-2 viremia in nursery piglets from a Spanish swine integration system in 2020 and 2022 considering PRRSV infection status.

Mònica Sagrera, Laura Garza-Moreno, Marina Sibila, Salvador Oliver-Ferrando, Sonia Cárceles, Carlos Casanovas, Patricia Prieto, Alberto García-Flores, David Espigares, Joaquim Segalés

Open access · goldAbstract read
In one paragraph

Article in Porcine health management, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Mònica Sagrera *IRTA. Programa de Sanitat Animal, Centre de Recerca en Sanitat Animal (CReSA, IRTA-UAB), Campus de La UAB, 08193, Bellaterra, Cerdanyola del Vallès, Spain.
Laura Garza-Moreno *Ceva Salud Animal, Avenida Diagonal, 609-615, 08028, Barcelona, Spain.
Marina SibilaIRTA. Programa de Sanitat Animal, Centre de Recerca en Sanitat Animal (CReSA, IRTA-UAB), Campus de La UAB, 08193, Bellaterra, Cerdanyola del Vallès, Spain.
Salvador Oliver-FerrandoCeva Salud Animal, Avenida Diagonal, 609-615, 08028, Barcelona, Spain.
Sonia CárcelesCeva Salud Animal, Avenida Diagonal, 609-615, 08028, Barcelona, Spain.
Carlos CasanovasCeva Salud Animal, Avenida Diagonal, 609-615, 08028, Barcelona, Spain.
Patricia PrietoInga Food S.A., Ronda de Poniente, 9, 28760, Tres Cantos, Madrid, Spain.
Alberto García-FloresInga Food S.A., Ronda de Poniente, 9, 28760, Tres Cantos, Madrid, Spain.
David EspigaresCeva Salud Animal, Avenida Diagonal, 609-615, 08028, Barcelona, Spain.
Joaquim SegalésUnitat Mixta d'Investigació IRTA-UAB en Sanitat Animal, Centre de Recerca en Sanitat Animal (CReSA), Campus de la Universitat Autònoma de Barcelona (UAB), 08193, Bellaterra, Barcelona, Spain. Joaquim.segales@irta.cat.
Clínica Diagonal · ESInstitute of Agrifood Research and Technology · ESUniversitat Autònoma de Barcelona · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPorcine circovirus 2 (PCV-2) poses a significant economic threat for the swine industry, causing a range of diseases collectively referred to as porcine circovirus diseases (PCVDs). Despite PCV-2 vaccine effectiveness, the need for monitoring infectious pressure remains. PCV-2 coinfection with other pathogens like porcine reproductive and respiratory syndrome virus (PRRSV) can exacerbate disease severity and lead to PCV-2-systemic disease cases. Monitoring both PRRSV and PCV-2 in co-infected farms is crucial for an effective management and vaccination programs. The present cross-sectional study aimed to determine PCV-2 antibody levels in piglets at weaning and PCV-2 and PRRSV viremia in pooled serum samples at weaning (vaccination age) and at 6 and 9 weeks of age from a Spanish swine integration system in 2020 (48 farms) and in 2022 (28 out of the 48 analysed previously).

resultsThe frequency of PCV-2 detection in pools of piglet sera was 2.1% (2020) and 7.1% (2022) at vaccination age but increased at the end of the nursery period (10.4% in 2020 and 39.3% in 2022) in both years. Co-infections between PCV-2 and PRRSV were detected in a significant proportion of PRRSV positive farms (15% in 2020, and 60% in 2022). PCV-2 antibody levels (ELISA S/P ratios) at weaning were lower in PCV-2 qPCR positive farms at different sampling time-points (0.361 in 2020 and 0.378 in 2022) compared to PCV-2 qPCR negative ones (0.587 in 2020 and 0.541 in 2022). The 28 farms tested both years were classified in four different epidemiological scenarios depending on their PCV-2 virological status. Those PCV-2 qPCR negative farms in 2020 that turned to be positive in 2022 had a statistically significant increase of PRRSV RT-qPCR detection and a PCV-2 antibody levels reduction, facts that were not observed in the rest of the scenarios.

conclusionThis epidemiological study in farms from the same integration system determined the occurrence, in 2020 and in 2022, of PCV-2 and PRRSV infections in piglets during the nursery period by using pooled serum samples.

Indexed as

Detection frequencyPorcine circovirus 2 (PCV-2)Porcine reproductive and respiratory syndrome virus (PRRSV)SpainViremia

Identifiers

PMID38229182
PMCPMC10792786
OpenAlexW4390901362

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.