Evidence map›Paper›PMID 38228973›Full record

ArticleReproductive sciences (Thousand Oaks, Calif.)2024

Reproductive Outcomes of Conventional In Vitro Fertilization and Intracytoplasmic Sperm Injection in Patients with Non-Severe Male Infertility Across Poor and Different Sub-Optimal Ovarian Response Categories: A Cohort Study Based on 30,352 Fresh Cycles from 2009-2019.

Dina Jiesisibieke, Tian Tian, Xiaxuan Zhu, Shilin Fang, Nan Zhang, Jinxi Ma, Yuqi Xia, Rong Li, Ping Liu, Jie Qiao and 1 more

Abstract read
In one paragraph

Article in Reproductive sciences (Thousand Oaks, Calif.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Dina Jiesisibieke *Peking University Third Hospital, Beijing, 100191, China.
Tian Tian *Peking University Third Hospital, Beijing, 100191, China.
Xiaxuan ZhuPeking University Third Hospital, Beijing, 100191, China.
Shilin FangPeking University Third Hospital, Beijing, 100191, China.
Nan ZhangPeking University Third Hospital, Beijing, 100191, China.
Jinxi MaPeking University Third Hospital, Beijing, 100191, China.
Yuqi XiaPeking University Third Hospital, Beijing, 100191, China.
Rong LiPeking University Third Hospital, Beijing, 100191, China.
Ping LiuPeking University Third Hospital, Beijing, 100191, China.
Jie QiaoPeking University Third Hospital, Beijing, 100191, China.
Rui YangPeking University Third Hospital, Beijing, 100191, China. yrjeff@126.com.ORCID 0000-0002-6381-5202

Funding

Beijing Science and Technology Planning Project Z191100006619085Key Technologies Research and Development Program 2021YFC2700605National Natural Science Foundation of China 82171632
6 · The paper itself

Abstract

Due to the influence of economic, social and many other factors, there are more and more reproductive problems. Originally introduced for managing male factor infertility, intracytoplasmic sperm injection had become the most commonly used fertilization treatment in the world, with broadened indications including low oocyte yield, prior fertilization failure with conventional in vitro fertilization etc. However, academic evidence for better live-birth outcomes of intracytoplasmic sperm injection over conventional in vitro fertilization is limited. Thus, we aimed to compare the reproductive outcomes of conventional in vitro fertilization and intracytoplasmic sperm injection in patients with non-severe male factor infertility across poor and different sub-optimal ovarian response categories. The fertility rate, implantation rate, clinical pregnancy rate, live birth rate and other obstetric outcomes were mainly compared. Our results showed that independent of the number of oocytes retrieved, intracytoplasmic sperm injection significantly increased the fertilization rate, while conventional in vitro fertilization cycles showed a higher implantation rate, clinical pregnancy rate, and live birth rate. No differences were observed in most obstetric outcomes. Our study indicates that poor ovarian response is not an indication for intracytoplasmic sperm injection in couples with non-severe male infertility.

Indexed as

Fertilization in VitroInfertility, MalePregnancy RateSperm Injections, IntracytoplasmicAdultCohort StudiesFemaleHumansLive BirthMaleOvulation InductionPregnancyPregnancy OutcomeRetrospective StudiesTreatment OutcomeIntracytoplasmic sperm injectionIn vitro fertilizationLow ovarian responseNon-severe male infertilityObstetric outcomes

Identifiers

PMID38228973
PMCPMC11090916

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.