ArticleNature microbiology2024
Methane-dependent complete denitrification by a single Methylomirabilis bacterium.
Article in Nature microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- Article
- Versatile microbial community responsible for nitrate turnover in a carbonate aquifer in southwest Germany.FEMS microbiology ecology · 2026Article
- Syntrophic interactions driving anaerobic methane oxidation in deep-sea cold seeps revealed by DNA-SIP.iScience · 2026Article
- Decoding coral resistance to eutrophication through the association of hyper‑efficient denitrifiers as key microbial allies.Nature communications · 2026Article
- Microbially driven methane and sulfur cycling processes and coupling mechanisms in mangrove sediments.Environmental microbiome · 2026Article
- Artificial Intelligence for Microbial Isolation and Cultivation: Progress and Challenges.Microorganisms · 2026Review
- Spatially resolved denitrification coupled with methane and arsenite oxidation at the millimeter-scale straw-soil interface.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Isolation and Characterization of a Novel Sulfur-OxidizingMicroorganisms · 2026Article
- Review
- Metagenomic sequencing reveals structural and functional differentiation of rhizosphere bacterial communities driven by nitrogen and potassium deficiency associated with root rot ofFrontiers in microbiology · 2026Article
- Article
- Environment selected microbial function rather than taxonomic species in a plateau saline-alkaline wetland.Applied and environmental microbiology · 2025Article
- Anaerobic methane oxidation coupled with denitrification mitigates soil nitrous oxide emissions.Science advances · 2025Article
- Cold seeps are potential hotspots of deep-sea nitrogen loss driven by microorganisms across 21 phyla.Nature communications · 2025Article
- Article
- Iron Oxides Fuel Anaerobic Oxidation of Methane in the Presence of Sulfate in Hypersaline Coastal Wetland Sediment.Environmental science & technology · 2025Article
- Growth of microbes in competitive lifestyles promotes increased ARGs in soil microbiota: insights based on genetic traits.Microbiome · 2025Article
- Microbial communities and metabolic functions vary with spatial heterogeneity in cold-seep carbonates.ISME communications · 2025Article
- Biochemical, physicochemical property and archaea community characteristics in casing soil of cultivatingFrontiers in microbiology · 2025Article
- Regulators of aerobic and anaerobic methane oxidation in two pristine temperate peatland types.FEMS microbiology ecology · 2024Article
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
Methane-dependent nitrate and nitrite removal in anoxic environments is thought to rely on syntrophy between ANME-2d archaea and bacteria in the genus 'Candidatus Methylomirabilis'. Here we enriched and purified a single Methylomirabilis from paddy soil fed with nitrate and methane, which is capable of coupling methane oxidation to nitrate reduction via nitrite to dinitrogen independently. Isotope labelling showed that this bacterium we name 'Ca. Methylomirabilis sinica' stoichiometrically performed methane-dependent complete nitrate reduction to dinitrogen gas. Multi-omics analyses collectively demonstrated that 'M. sinica' actively expressed a well-established pathway for this process, especially including nitrate reductase Nap. Furthermore, 'M. sinica' exhibited a higher nitrate affinity than most denitrifiers, implying its competitive fitness under oligotrophic nitrogen-limited conditions. Our findings revise the paradigm of methane-dependent denitrification performed by two organisms, and the widespread presence of 'M. sinica' in public databases suggests that the coupling of methane oxidation and complete denitrification in single cells substantially contributes to global methane and nitrogen budgets.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.