Evidence map›Paper›PMID 38228727›Full record

SynthesisNature human behaviour2024

A systematic review and meta-analysis of transdiagnostic cognitive behavioural therapies for emotional disorders.

Carmen Schaeuffele, Laura E Meine, Ava Schulz, Maxi C Weber, Angela Moser, Christina Paersch, Dominique Recher, Johanna Boettcher, Babette Renneberg, Christoph Flückiger and 1 more

Open access · hybridAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Nature human behaviour, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 4 pooled it
33.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 4 syntheses or guidelines pooled it, 66 citations in OpenAlex.

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  20. Innovations to improve outcomes and uptake of psychotherapies for mental disorders: a state-of-the-art review.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 3 countries.

Carmen Schaeuffele *Department of Education and Psychology, Freie Universitaet Berlin, Berlin, Germany. carmen.schaeuffele@fu-berlin.de.ORCID 0000-0001-5902-0725
Laura E Meine *Experimental Psychopathology and Psychotherapy, Department of Psychology, University of Zurich, Zurich, Switzerland. laura.meine@bli.uzh.ch.ORCID 0000-0002-2894-9918
Ava Schulz *Experimental Psychopathology and Psychotherapy, Department of Psychology, University of Zurich, Zurich, Switzerland.
Maxi C WeberDepartment of Education and Psychology, Freie Universitaet Berlin, Berlin, Germany.
Angela MoserExperimental Psychopathology and Psychotherapy, Department of Psychology, University of Zurich, Zurich, Switzerland.
Christina PaerschExperimental Psychopathology and Psychotherapy, Department of Psychology, University of Zurich, Zurich, Switzerland.
Dominique RecherExperimental Psychopathology and Psychotherapy, Department of Psychology, University of Zurich, Zurich, Switzerland.ORCID 0000-0002-9803-7834
Johanna BoettcherClinical Psychology and Psychotherapy, Psychologische Hochschule Berlin, Berlin, Germany.
Babette RennebergDepartment of Education and Psychology, Freie Universitaet Berlin, Berlin, Germany.
Christoph FlückigerDepartment of Psychology, University of Kassel, Kassel, Germany.
Birgit KleimExperimental Psychopathology and Psychotherapy, Department of Psychology, University of Zurich, Zurich, Switzerland.
University of Zurich · CHFreie Universität Berlin · DEPsychologische Hochschule Berlin · DEUniversity of Bern · CHUniversity of Kassel · DE

Funding

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (Swiss National Science Foundation) 169827
6 · The paper itself

Abstract

Transdiagnostic cognitive behavioural psychotherapy (TD-CBT) may facilitate the treatment of emotional disorders. Here we investigate short- and long-term efficacy of TD-CBT for emotional disorders in individual, group and internet-based settings in randomized controlled trials (PROSPERO CRD42019141512). Two independent reviewers screened results from PubMed, MEDLINE, PsycINFO, Google Scholar, medRxiv and OSF Preprints published between January 2000 and June 2023, selected studies for inclusion, extracted data and evaluated risk of bias (Cochrane risk-of-bias tool 2.0). Absolute efficacy from pre- to posttreatment and relative efficacy between TD-CBT and control treatments were investigated with random-effects models. Of 56 identified studies, 53 (6,705 participants) were included in the meta-analysis. TD-CBT had larger effects on depression (g = 0.74, 95% CI = 0.57-0.92, P < 0.001) and anxiety (g = 0.77, 95% CI = 0.56-0.97, P < 0.001) than did controls. Across treatment formats, TD-CBT was superior to waitlist and treatment-as-usual. TD-CBT showed comparable effects to disorder-specific CBT and was superior to other active treatments for depression but not for anxiety. Different treatment formats showed comparable effects. TD-CBT was superior to controls at 3, 6 and 12 months but not at 24 months follow-up. Studies were heterogeneous in design and methodological quality. This review and meta-analysis strengthens the evidence for TD-CBT as an efficacious treatment for emotional disorders in different settings.

Indexed as

Cognitive Behavioral TherapyAnxiety DisordersHumans

Identifiers

PMID38228727
PMCPMC10963275
OpenAlexW4390918459

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.