ArticleScientific reports2024
Reductions in sustained prescription opioid use within the US between 2017 and 2021.
Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 19 citations in OpenAlex.
- Collaborative care intervention for risky opioid use among primary care patients: The STOP randomized clinical trial.Addiction (Abingdon, England) · 2026Trial
- Strategies to Deimplement Opioid Prescribing in Primary Care: A Cluster Randomized Clinical Trial.JAMA network open · 2024Trial
- Nationwide Trends in Opioid Consumption in Costa Rica, 2017-2024: Implications for Regulatory Policy and Public Health.Pharmacoepidemiology and drug safety · 2026Article
- Chronic opioid prescription rates following long-segment lumbar instrumentation: A comparison of academic and nonacademic centers.North American Spine Society journal · 2026Article
- Trends in acupuncture billing by a large commercial insurer.The American journal of managed care · 2026Article
- Suzetrigine: What Should Plastic Surgeons Know?Plastic and reconstructive surgery. Global open · 2026Article
- Opioid overdose associated with concomitant use of hydrocodone and selective serotonin reuptake inhibitors.BMC medicine · 2025Article
- Is Civilian Hospital Treatment of Lumbar Spinal Disorders Associated With Greater Odds of Fusion Procedures?Clinical orthopaedics and related research · 2025Article
- Understanding the first prescription: clinical and demographic drivers of strong opioid use in primary care.Pain medicine (Malden, Mass.) · 2025Article
- Opioid Dependence Increases Complications and Costs Following Lumbar Spinal Fusion: Insights from a Nationwide Database.Journal of clinical medicine · 2025Article
- Prescription opioid use and substance use disorder in US women (2006-2022): a retrospective cohort study.Lancet regional health. Americas · 2025Article
- Global, regional, and national burden of disease analysis on paralytic ileus and intestinal obstruction in adults aged 65 and over from 1990 to 2021, with projections for 2030: a Global Burden of Disease Study 2021 analysis.BMC gastroenterology · 2025Article
- Chronic Opioid Use After Implementation of Oregon's Medicaid Back Pain Policy.American journal of preventive medicine · 2025Article
- Long-term prescription opioid use following surgery in the US (2017-2022): a population-based study.Lancet regional health. Americas · 2024Article
- Opioid use in cancer patients compared with noncancer pain patients in a veteran population.JNCI cancer spectrum · 2024Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
Over the last decade, various efforts have been made to curtail the opioid crisis. The impact of these efforts, since the onset of the COVID-19 pandemic, has not been well characterized. We sought to develop national estimates of the prevalence of sustained prescription opioid use for a time period spanning the COVID-19 pandemic (2017-2021). We used TRICARE claims data (fiscal year 2017-2021) to identify patients who were prescription opioid non-users prior to receipt of a new opioid medication. We evaluated eligible patients for subsequent sustained prescription opioid use. The prevalence of sustained prescription opioid use during 2020-2021 was compared to 2017-2019. We performed multivariable logistic regression analyses to adjust for confounding. We performed secondary analyses that accounted for interactions between the time period and age, as well as a proxy for socioeconomic status. We determined there was a 68% reduction in the odds of sustained prescription opioid use (OR 0.32; 95% CI 0.27, 0.38; p < 0.001) in 2020-2021 as compared to 2017-2019. Significant reductions were identified across all US census divisions and all patient age groups. In both time periods, the plurality of encounters associated with initial receipt of an opioid that culminated in sustained prescription opioid use were associated with non-specific primary diagnoses. We found significant reductions in sustained prescription opioid use in 2020-2021 as compared to 2017-2019. The persistence of prescribing behaviors that result in issue of opioids for poorly characterized conditions remains an area of concern.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.