ArticleScientific reports2024
Isolation and characterization of novel Bacillus strains with superior probiotic potential: comparative analysis and safety evaluation.
Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
46 citing papers in PubMed, 58 citations in OpenAlex.
- Alleviating symptoms of paediatric acute rhinosinusitis and acute otitis media with otorrhea using nasal-spraying Bacillus probiotics: a randomized controlled trial.Scientific reports · 2025Trial
- Evaluation of Indigenous Bacillus Strains from Asian Fermented Foods for Probiotic Properties.Probiotics and antimicrobial proteins · 2026Article
- Safety Evaluation ofFood science & nutrition · 2026Article
- High Probiotic Potential of Soil-Derived Bacillus safensis, Bacillus pumilus and Bacillus zhangzhouensis Strains: In Vitro Safety Assessment and Functional Characterization.Probiotics and antimicrobial proteins · 2026Article
- Innovative Approaches Against Planktonic and Biofilm-ProducingVeterinary sciences · 2026Review
- Identification ofFoods (Basel, Switzerland) · 2026Article
- Overcoming cellular secretion bottlenecks: advanced secretion engineering and molecular tailoring for next-generation microbial α-amylases with enhanced industrial performance.World journal of microbiology & biotechnology · 2026Review
- Aroma compound production and probiotic functionality of Bacillus paralicheniformis isolates from Berma, a fermented fish product of Tripura, India.Scientific reports · 2026Article
- Characterization ofAnimals : an open access journal from MDPI · 2026Article
- Antioxidant capacity, and probiotic properties of Enterococcus faecium strains isolated from raw milk of indigenous brown atlas cows.Antonie van Leeuwenhoek · 2026Article
- Development of an Integrated Screening Framework for Marine-DerivedMarine drugs · 2026Article
- Genomic and Phenotypic Evaluation of the Gliadin-Degrading Probiotic Bacillus amyloliquefaciens EG025 from Cheonggukjang for Celiac Disease Treatment.Probiotics and antimicrobial proteins · 2026Article
- Microorganism-Based Biological Products for Agriculture: From Strain Selection to Production Organization.Microorganisms · 2026Review
- Bacillus spore probiotics for alleviating functional constipation in children: a randomized, double-blind, placebo-controlled trial.Communications medicine · 2026Article
- GCMS and Molecular Docking Based Insights into the Antifungal Potential of Bacillus Bs-06 Against Fusarium oxysporum f. sp. lycopersici.The protein journal · 2026Article
- Biotransformation of Aliphatic and Aromatic Hydrocarbons by Aerobic Bacterial Strains Isolated from Brown Coal.International journal of molecular sciences · 2026Article
- Metagenomic analysis of the gut microbiota inFrontiers in microbiology · 2026Article
- Probiotic properties ofFrontiers in microbiology · 2026Article
- Anti-inflammatory effect of aFrontiers in microbiology · 2026Article
- Biocontrol efficiency of nativeCurrent research in microbial sciences · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
Despite the current use of some Bacillus spp. as probiotics, looking for and introducing new efficient and safe potential probiotic strains is one of the most important topics in both microbiology and food industry. This study aimed to isolate, identify, and evaluate the probiotic characteristics and safety of some Bacillus spp. from natural sources. Thirty-six spore-forming, Gram-positive, and catalase-positive Bacillus isolates were identified in 54 samples of soil, feces and dairy products. Bacterial identification was performed using 16S rDNA sequencing. To evaluate the probiotic potential of isolates, the resistance of bacterial cells to simulated gastrointestinal tract (GIT) conditions, the presence of enterotoxin genes, their susceptibility to antibiotics, antimicrobial and hemolytic activities and biochemical profiles were investigated. The results revealed that eight sporulating Bacillus spp. isolates fulfilled all tested probiotic criteria. They showed a high growth rate, non-hemolytic and lecithinase activity, and resistance to simulated GIT conditions. These strains exhibited broad-spectrum antibacterial activity against pathogenic bacteria. In addition, they did not exhibit antibacterial resistance to the 12 tested antibiotics. The results of this study suggest that these isolates can be considered as candidates for functional foods and as safe additives to improve diet quality.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.