Evidence map›Paper›PMID 38228093›Full record

ReviewThe Journal of urology2024

Cognitive Behavioral Therapy for Chronic Pelvic Pain: What Is It and Does It Work?

Jeffrey M Lackner, J Quentin Clemens, Christopher Radziwon, Teresa L Danforth, Tova S Ablove, Susan S Krasner, Alison M Vargovich, Patricia C O'Leary, Tracy Marotto, Bruce D Naliboff

Open access · greenAbstract readReview
In one paragraph

Review in The Journal of urology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 16 citations in OpenAlex.

  1. Pelvic floor rehabilitation in cancer survivorship: an umbrella review.Journal of cancer survivorship : research and practice · 2026
    Pooled it
  2. Pooled it
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  10. Virtual Reality Interventions and Chronic Pain: Scoping Review.Journal of medical Internet research · 2025
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Jeffrey M LacknerDivision of Behavioral Medicine, Department of Medicine, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, New York.ORCID 0000-0002-9717-1353
J Quentin ClemensDepartment of Urology, University of Michigan, Ann Arbor, Michigan.
Christopher RadziwonDivision of Behavioral Medicine, Department of Medicine, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, New York.
Teresa L DanforthDepartment of Urology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, New York.
Tova S AbloveDepartment of Obstetrics and Gynecology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, New York.
Susan S KrasnerDivision of Behavioral Medicine, Department of Medicine, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, New York.
Alison M VargovichDivision of Behavioral Medicine, Department of Medicine, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, New York.
Patricia C O'LearyDivision of Behavioral Medicine, Department of Medicine, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, New York.
Tracy MarottoDivision of Behavioral Medicine, Department of Medicine, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, New York.
Bruce D NaliboffG. Oppenheimer Center for Neurobiology of Stress and Resilience, Department of Medicine, University of California, Los Angeles, Los Angeles, California.
University at Buffalo, State University of New York · USUniversity of California, Los Angeles · USUniversity of Michigan · US

Funding

A BRIEF, TRANSDIAGNOSTIC COGNITIVE BEHAVIORAL TREATMENT FOR UROLOGIC CHRONIC PELVIC PAIN SYNDROME (UCPPS): PROCESS, PREDICTIONS, OUTCOMESR01DK128927 · NIDDK · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI LACKNER, JEFFREY M · 2021 to 2025
$3.3M
Neurobiological mechanisms underlying effectiveness of CBT in IBS patientsR01DK096606 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LACKNER, JEFFREY M, MAYER, EMERAN A · 2012 to 2015
$1.9M
NIDDK NIH HHS R01 DK096606NIDDK NIH HHS R01 DK128927
6 · The paper itself

Abstract

purposeUrologic chronic pelvic pain syndrome (UCPPS), which encompasses interstitial cystitis/bladder pain syndrome in women and men and chronic prostatitis/chronic pelvic pain syndrome in men, is a common, often disabling urological disorder that is neither well understood nor satisfactorily treated with medical treatments. The past 25 years have seen the development and validation of a number of behavioral pain treatments, of which cognitive behavioral therapy (CBT) is arguably the most effective. CBT combines strategies of behavior therapy, which teaches patients more effective ways of behaving, and cognitive therapy, which focuses on correcting faulty thinking patterns. As a skills-based treatment, CBT emphasizes "unlearning" maladaptive behaviors and thoughts, and replacing them with more adaptive ones that support symptom self-management. MATERIALS AND

methodsThis review describes the rationale, technical procedures, and empirical basis of CBT.

resultsWhile evidence supports CBT for treatment-refractory chronic pain disorders, there is limited understanding of why or how CBT might work, for whom it is most beneficial, or the specific UCPPS symptoms (eg, pain, urinary symptoms) it effectively targets. This is the focus of EPPIC (Easing Pelvic Pain Interventions Clinical Research Program), a landmark NIH trial examining the efficacy of low-intensity, home-based CBT for UCPPS relative to a nonspecific comparator featuring self-care recommendations of AUA guidelines.

conclusionsSystematic efforts to increase both the efficiency of CBT and the way it is delivered (eg, home-based treatments) are critical to scaling up CBT, optimizing its therapeutic potential, and reducing the public health burden of UCPPS.

Indexed as

Chronic PainCognitive Behavioral TherapyCystitis, InterstitialFemaleHumansMalePelvic PainSyndrome

Identifiers

PMID38228093
PMCPMC10939861
OpenAlexW4390901407

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.