Evidence map›Paper›PMID 38227930›Full record

ArticleACS biomaterials science & engineering2024

Fabrication of a Low Cost Superhydrophobic Substrate for Surface Enhanced Laser-Induced Breakdown Spectroscopy and Its Utility through Identification of Electrolyte Variation for Oral Cancer Detection.

Keerthi K, Sajan Daniel George, Ravikiran Ongole, Unnikrishnan V K

Open access · hybridAbstract read
In one paragraph

Article in ACS biomaterials science & engineering, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 10 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Keerthi KDepartment of Atomic and Molecular Physics, Manipal Academy of Higher Education, Manipal-576104, India.
Sajan Daniel GeorgeDepartment of Atomic and Molecular Physics, Manipal Academy of Higher Education, Manipal-576104, India.ORCID 0000-0003-4198-2613
Ravikiran OngoleDepartment of Oral Medicine and Radiology, Manipal College of Dental Sciences, Manipal Academy of Higher Education, Mangalore- 575001, India.
Unnikrishnan V KDepartment of Atomic and Molecular Physics, Manipal Academy of Higher Education, Manipal-576104, India.ORCID 0000-0003-3907-0586
Manipal Academy of Higher Education · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ultratrace elemental detections from a limited volume of samples can offer significant benefits in biomedical fields. However, it can be challenging to concentrate the particles being analyzed in a small area to improve the accuracy of detection. Ring-like deposits on the edges of colloidal droplets are a vexing problem in many applications. Herein, we report ultratrace elemental detection using a superhydrophobic surface-enhanced laser-induced breakdown spectroscopy (SELIBS) substrate fabricated by laser ablation followed by a soft lithography technique. In this work, the SELIBS spectra on a superhydrophobic polydimethylsiloxane (PDMS) substrate replicated from a laser-patterned master Teflon substrate are investigated. This work highlights the application of this newly created superhydrophobic substrate for detecting trace elements in body fluids using SELIBS. The developed PDMS substrate was successfully adopted to investigate the electrolyte variation in serum samples of oral cancer patients and normal volunteers. Principal component analysis (PCA) and match-no-match analysis were used to distinguish the elemental variation in cancer and control groups.

Indexed as

DimethylpolysiloxanesMouth NeoplasmsElectrolytesHumansHydrophobic and Hydrophilic InteractionsSpectrum AnalysisbaysilonDimethylpolysiloxanesElectrolytesbiomedical sensingnanostructured materialoral cancerSELIBSsuperhydrophobic PDMS

Identifiers

PMID38227930
PMCPMC10865284
OpenAlexW4390902003

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.