Evidence map›Paper›PMID 38227706›Full record

ArticleVeterinary medicine and science2024

Subcutaneous leiomyosarcoma in a cynomolgus macaque (Macaca fascicularis).

Dong-Ho Lee, Jun Won Mo, Seung-Bin Yoon, Jeongwoo Kwon, Yu-Jin Jo, Sang Il Lee, Taeho Kwon, Jungkee Kwon, Ji-Su Kim

Open access · goldAbstract readCase Reports
In one paragraph

Article in Veterinary medicine and science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Dong-Ho LeePrimate Resources Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Jeongeup, Jeonbuk, Republic of Korea.ORCID 0009-0005-5528-026X
Jun Won MoPrimate Resources Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Jeongeup, Jeonbuk, Republic of Korea.
Seung-Bin YoonPrimate Resources Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Jeongeup, Jeonbuk, Republic of Korea.ORCID 0000-0002-0056-4995
Jeongwoo KwonPrimate Resources Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Jeongeup, Jeonbuk, Republic of Korea.ORCID 0000-0001-9214-7170
Yu-Jin JoPrimate Resources Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Jeongeup, Jeonbuk, Republic of Korea.ORCID 0000-0002-9067-3537
Sang Il LeePrimate Resources Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Jeongeup, Jeonbuk, Republic of Korea.
Taeho KwonPrimate Resources Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Jeongeup, Jeonbuk, Republic of Korea.ORCID 0000-0001-9489-0283
Jungkee KwonDepartment of Laboratory Animal Medicine, College of Veterinary Medicine, Jeonbuk National University, Iksan, Jeonbuk, Republic of Korea.
Ji-Su KimPrimate Resources Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Jeongeup, Jeonbuk, Republic of Korea.
Korea Research Institute of Bioscience and Biotechnology · KR

Funding

Korea Research Institute of Bioscience and Biotechnology (KRIBB) Research Initiative Program, KGM5162423
6 · The paper itself

Abstract

Leiomyosarcoma, a malignant tumour originating from smooth muscle cells, has rarely been documented in non-human primates. In this case study, a 7-year-old female cynomolgus macaque (Macaca fascicularis) presented with a rapidly growing mass overlying the left elbow joint. Radiographs indicated the presence of a soft tissue neoplasm without any associated bone involvement. The mass was surgically resected. Histological and immunohistochemical analyses revealed spindle-shaped cells with eosinophilic cytoplasm that resembled smooth muscle cells, exhibiting positive immunoreactions for vimentin, desmin and smooth muscle actin and a negative reaction for pan-cytokeratin. This is the first reported case of subcutaneous leiomyosarcoma in a cynomolgus macaque and provides important insights into the incidence and characteristics of this condition in this species.

Indexed as

LeiomyosarcomaSoft Tissue NeoplasmsAnimalsFemaleMacaca fascicularisVimentinVimentincynomolgus macaqueleiomyosarcomaMacacasmooth muscle cellssoft tissue neoplasm

Identifiers

PMID38227706
PMCPMC10790726
OpenAlexW4390904222

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.