Evidence map›Paper›PMID 38227196›Full record

ArticleNaunyn-Schmiedeberg's archives of pharmacology2024

Insight into the mechanism of action of ORG27569 at the cannabinoid type one receptor utilising a unified mathematical model.

Hayley M Green, Liang Yang, Xiao Zhu, David B Finlay, Stephen B Duffull, Michelle Glass

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Naunyn-Schmiedeberg's archives of pharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Hayley M GreenDepartment of Pharmacology and Toxicology, School of Biomedical Sciences, University of Otago, PO Box 56, Dunedin, 9054, New Zealand.
Liang YangOtago Pharmacometrics Group, School of Pharmacy, University of Otago, Dunedin, New Zealand.
Xiao ZhuDepartment of Clinical Pharmacy and Pharmacy Administration, School of Pharmacy, Fudan University, Shanghai, China.
David B FinlayDepartment of Pharmacology and Toxicology, School of Biomedical Sciences, University of Otago, PO Box 56, Dunedin, 9054, New Zealand.
Stephen B DuffullOtago Pharmacometrics Group, School of Pharmacy, University of Otago, Dunedin, New Zealand.
Michelle GlassDepartment of Pharmacology and Toxicology, School of Biomedical Sciences, University of Otago, PO Box 56, Dunedin, 9054, New Zealand. michelle.glass@otago.ac.nz.
University of Otago · NZFudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Allosteric modulation of CB

Indexed as

Cyclic AMPModels, TheoreticalPiperidinesReceptor, Cannabinoid, CB1Allosteric RegulationCannabinoid Receptor AgonistsCyclohexanolsHEK293 CellsHumansIndoles3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol5-chloro-3-ethyl-1H-indole-2-carboxylic acid (2-(4-piperidin-1-yl-phenyl)ethyl)amideCannabinoid Receptor AgonistsCyclic AMPCyclohexanolsIndolesPiperidinesReceptor, Cannabinoid, CB1Cannabinoid type 1 receptorCyclic adenosine monophosphate (cAMP)ORG27569

Identifiers

PMID38227196
PMCPMC11166842
OpenAlexW4390913854

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.