Evidence map›Paper›PMID 38227165›Full record

ArticleDrug delivery and translational research2024

Nanoemulsions and nanocapsules loaded with Melaleuca alternifolia essential oil for sepsis treatment.

Mariana Alves Battisti, Larissa Constantino, Débora Fretes Argenta, Flávio Henrique Reginatto, Felipe Dal Pizzol, Thiago Caon, Angela Machado Campos

Abstract read
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In one paragraph

Article in Drug delivery and translational research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Recent nanoengineered therapeutic advancements in sepsis management.Frontiers in bioengineering and biotechnology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Mariana Alves BattistiPostgraduate Program in Pharmacy (PGFAR), Department of Pharmaceutical Sciences, Federal University of Santa Catarina, Campus Universitário, Trindade, 88040-900, Florianópolis, SC, Brazil.
Larissa ConstantinoPostgraduate Program in Pharmacy (PGFAR), Department of Pharmaceutical Sciences, Federal University of Santa Catarina, Campus Universitário, Trindade, 88040-900, Florianópolis, SC, Brazil.
Débora Fretes ArgentaPostgraduate Program in Pharmacy (PGFAR), Department of Pharmaceutical Sciences, Federal University of Santa Catarina, Campus Universitário, Trindade, 88040-900, Florianópolis, SC, Brazil.
Flávio Henrique ReginattoPostgraduate Program in Pharmacy (PGFAR), Department of Pharmaceutical Sciences, Federal University of Santa Catarina, Campus Universitário, Trindade, 88040-900, Florianópolis, SC, Brazil.
Felipe Dal PizzolLaboratory of Experimental Pathophysiology, Postgraduate Program in Health Sciences, University of South Santa Catarina, Criciúma, Brazil.
Thiago CaonPostgraduate Program in Pharmacy (PGFAR), Department of Pharmaceutical Sciences, Federal University of Santa Catarina, Campus Universitário, Trindade, 88040-900, Florianópolis, SC, Brazil.
Angela Machado CamposPostgraduate Program in Pharmacy (PGFAR), Department of Pharmaceutical Sciences, Federal University of Santa Catarina, Campus Universitário, Trindade, 88040-900, Florianópolis, SC, Brazil. angela.campos@ufsc.br.ORCID 0000-0001-8936-3059
Universidade Federal de Santa Catarina · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sepsis represents a complex clinical syndrome that results from a harmful host response to infection. The infections most associated with sepsis are pneumonia, intra-abdominal infection, and urinary tract infection. Tea tree oil (TTO) has shown high antibacterial activity; however, it exhibits low aqueous solubility and high volatility, which have motivated its nanoencapsulation. In this study, the performance of nanoemulsions (NE) and nanocapsules (NC) loaded with TTO was compared. These systems were prepared by spontaneous emulsification and nanoprecipitation methods, respectively. Poly-ε-caprolactone or Eudragit

Indexed as

MelaleucaNanocapsulesPolymethacrylic AcidsSepsisTea Tree OilPoloxamermethylmethacrylate-methacrylic acid copolymerNanocapsulesPoloxamerPolymethacrylic AcidsTea Tree OilMelaleuca alternifoliaNanocapsulesNanoemulsionSepsisTea tree oil

Identifiers

PMID38227165
OpenAlexW4390919415

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.