ArticleArchives of Razi Institute2023
Evaluation of the Effects of Amoxicillin on Tooth Development in Rats by Histological and Histomorphometric Study.
Article in Archives of Razi Institute, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.
- Effects of Antibiotics and Anti-Inflammatory Drugs on Enamel Development: A Systematic Review with Quantitative Synthesis.International dental journal · 2026Pooled it
- Evaluation of titanium-prepared platelet-rich fibrin incorporated with amoxiclav, metronidazole, and neem gel on bone regeneration in Wistar rats: a pilot study.Journal of the Korean Association of Oral and Maxillofacial Surgeons · 2026Article
- Penicillin Disrupts Dental Mineralization in Rats: A Comparative Study With Tetracycline Highlighting Prenatal and Postnatal Risks.Clinical and experimental dental research · 2025Article
- Prolonged early-life antibiotic exposure alters gut microbiota but does not exacerbate lung injury in a rat pup model.Pediatric research · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Amoxicillin is one of the most commonly prescribed antibiotics in children. As a result, it is prescribed as the first line of defence against cutaneous, gastrointestinal, and respiratory infections. The objective of this study was to evaluate the effects of Amoxicillin on the formation of dentin and enamel during the secretory and early phases of mineralization. Regarding the materials and methods used to perform this study, 16 pregnant adult Wistar rats were equally divided into two groups. The first group did not receive the drug and was prescribed a saline solution (control group), and the other group received 250 mg/kg/day of Amoxicillin (experimental group). From the 13
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.