Evidence map›Paper›PMID 38226210›Full record

ReviewHeliyon2024

Relationship between long non-coding RNAs and Hippo signaling pathway in gastrointestinal cancers; molecular mechanisms and clinical significance.

Farimah Fayyaz, Zahra Shokati Eshkiki, Amir Reza Karamzadeh, Zahra Moradi, Faezeh Kaviani, Abolfazl Namazi, Roya Karimi, Seidamir Pasha Tabaeian, Fatemeh Mansouri, Abolfazl Akbari

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Farimah FayyazColorectal Research Center, Iran University of Medical Sciences, Tehran, Iran.
Zahra Shokati EshkikiAlimentary Tract Research Center, Clinical Sciences Research Institute, Imam Khomeini Hospital, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Amir Reza KaramzadehOccupational Medicine Research Center, Iran University of Medical Sciences, Tehran, Iran.
Zahra MoradiDepartment of Genetic, Faculty of Sciences, Qom Branch, Islamic Azad University, Qom, Iran.
Faezeh KavianiDepartment of Genetic, Faculty of Sciences, Qom Branch, Islamic Azad University, Qom, Iran.
Abolfazl NamaziColorectal Research Center, Iran University of Medical Sciences, Tehran, Iran.
Roya KarimiColorectal Research Center, Iran University of Medical Sciences, Tehran, Iran.
Seidamir Pasha TabaeianColorectal Research Center, Iran University of Medical Sciences, Tehran, Iran.
Fatemeh MansouriDepartment of Genetic, Faculty of Sciences, Qom Branch, Islamic Azad University, Qom, Iran.
Abolfazl AkbariColorectal Research Center, Iran University of Medical Sciences, Tehran, Iran.
Iran University of Medical Sciences · IRQom Islamic Azad University · IRAhvaz Jundishapur University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Long non-coding RNAs (lncRNAs) play a significant biological role in the regulation of various cellular processes such as cell proliferation, differentiation, apoptosis and migration. In various malignancies, lncRNAs interplay with some main cancer-associated signaling pathways, including the Hippo signaling pathway to regulate the various cellular processes. It has been revealed that the cross-talking between lncRNAs and Hippo signaling pathway involves in gastrointestinal (GI) cancers development and progression. Considering the clinical significance of these lncRNAs, they have also been introduced as potential biomarkers in diagnostic, prognostic and therapeutic strategies in GI cancers. Herein, we review the mechanisms of lncRNA-mediated regulation of Hippo signaling pathway and focus on the corresponding molecular mechanisms and clinical significance of these non-coding RNAs in GI cancers.

Indexed as

DiagnosisGastrointestinal cancersHippoLong non-coding RNAPrognosisSignaling pathway

Identifiers

PMID38226210
PMCPMC10788524
OpenAlexW4390084257

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.