ArticleWorld journal of plastic surgery2023
A Case of Refractory Heel Ulcer Complicated by Moderate Osteomyelitis and Cellulitis Successfully Treated with Rheocarna.
Article in World journal of plastic surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 4 citations in OpenAlex.
- Successful Treatment of Refractory Bilateral Leg Ulcers With an Adsorptive Blood-Purification Device.Plastic and reconstructive surgery. Global open · 2025Article
- The Effectiveness of Low-Density Lipoprotein/Fibrinogen Apheresis in Promoting Wound Healing of No-Option Chronic Limb-Threatening Ischemia Foot Ulcers with Wound, Ischemia, and Foot Infection (WIfI) Wound Grade 3: A Single-Center Retrospective Analysis.Journal of clinical medicine · 2025Article
- Rheocarna Effectively Treats Oral Medicinal Therapy-Resistant Cutaneous Symptoms and Renal Failure Induced by Cholesterol Crystal Embolism.Clinical case reports · 2024Article
- Prosthetic Gait Achievement in an Elderly Patient with Chronic Limb-threatening Ischemia and High Complications Using a Novel Lipoprotein Apheresis.Progress in rehabilitation medicine · 2024Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
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Abstract
Revascularization surgery was first considered for the treatment of ulcers in patients with critical limb ischemia (CLI). However, it may not be indicated for patients with severe infections or peripheral vascular occlusions. Although blood purification therapy is adjuvant therapy for such patients, it is not yet widely used due to insurance coverage. We report a case of a refractory heel ulcer with moderate osteomyelitis and cellulitis that was not amenable to revascularization. Treatment with the adsorptive blood purifier rheocarna® (Kaneka Corporation; Osaka, Japan) resulted in complete epithelialization of the ulcer and control of inflammation. Although this case required careful follow-up, we believe rheocarna might be a promising treatment option for patients with CLI who do not respond to revascularization. Rheocarna could improve peripheral blood flow and control inflammation by improving antibiotic drug delivery.
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