ReviewCureus2023
A Comprehensive Review of Treatment Strategies for Early Avascular Necrosis.
Review in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.
- Deep learning in the diagnosis, staging, and prognosis of osteonecrosis of the femoral head: a systematic review.BMC musculoskeletal disorders · 2026Pooled it
- A Stage-Based, Multidisciplinary Approach to Therapy-Associated Osteonecrosis in Pediatric Oncology Patients.Journal of the Pediatric Orthopaedic Society of North America · 2026Review
- Managing Complications of Total Hip Arthroplasty for Avascular Necrosis Hip Performed Via Anterior Approach.Journal of orthopaedic case reports · 2026Article
- Review
- When Chronic Pain Clouds Acute Diagnosis: Femoral Shaft Osteonecrosis With SuperimposedClinical case reports · 2026Article
- Article
- Risk factors for Kienböck's disease and need for surgical intervention: a nationwide register study from Finland.The Journal of hand surgery, European volume · 2026Article
- Bilateral Avascular Necrosis of the Femoral Head in a Patient With Sickle Cell Trait: A Case Report.Cureus · 2026Article
- Treatment for primary avascular necrosis of the lower limb in childhood.The Cochrane database of systematic reviews · 2026Article
- An in-depth examination of bone avascular necrosis and early-stage treatment modalities utilizing regenerative medicine.Iranian journal of basic medical sciences · 2026Review
- Evaluating the Readability of Online Patient Education Materials for Avascular Necrosis.Journal of patient-centered research and reviews · 2026Article
- Clinical, imaging, and histopathological characteristics of Vietnamese patients with late-stage avascular necrosis of the femoral head.BMC musculoskeletal disorders · 2025Article
- Dexamethasone-Induced Avascular Necrosis of the Femoral Head in a Patient With Major Depressive Disorder: A Rare Case Report.Clinical case reports · 2025Article
- Article
- Bilateral Avascular Necrosis of the Hips in a Patient With Sickle Cell Trait and Chronic Alcohol Use.Journal of hematology · 2025Article
- Article
- Stem cell-derived extracellular vesicles as a therapeutic for avascular necrosis: current status and future prospects.Regenerative medicine · 2025Review
- Risk Factors for Corticosteroid-associated Osteonecrosis in Children: A National Database Study.Journal of the Pediatric Orthopaedic Society of North America · 2025Article
- Article
- Could a Mediterranean Diet Modulate Alzheimer's Disease Progression? The Role of Gut Microbiota and Metabolite Signatures in Neurodegeneration.Foods (Basel, Switzerland) · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Avascular necrosis (AVN), characterised by compromised blood supply leading to bone necrosis, poses a significant challenge in orthopaedic and rheumatologic practice. This review comprehensively examines early AVN treatment strategies, including aetiology and risk factors, clinical presentation, conservative and surgical approaches, emerging therapies, and rehabilitation. Key findings underscore the importance of early detection, personalised treatment plans, and a multidisciplinary approach involving orthopaedic specialists, rheumatologists, and physical therapists. The implications for clinical practice emphasise individualised care, staying abreast of emerging therapies, and patient education. Recommendations for future management strategies highlight the need for imaging technology advancements, regenerative therapies integration, and ongoing research into genetic and molecular pathways. As the field continues to evolve, translating research findings into clinical practice holds promise for improving outcomes and enhancing the overall quality of life for individuals affected by AVN.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.