Evidence map›Paper›PMID 38226012›Full record

ArticleMaterials today. Bio2024

Live macrophages loaded with Fe

Li Ruan, Xinxi Cai, Rui Qian, Shifang Bei, Lin Wu, Jin Cao, Song Shen

Open access · goldAbstract read
In one paragraph

Article in Materials today. Bio, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Iron metabolism in rheumatic diseases.Journal of translational autoimmunity · 2025
    Review
  5. Review
  6. Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Li RuanAffiliated Hospital of Jiangsu University, Zhenjiang, 212001, China.
Xinxi CaiAffiliated Hospital of Jiangsu University, Zhenjiang, 212001, China.
Rui QianAffiliated Hospital of Jiangsu University, Zhenjiang, 212001, China.
Shifang BeiThe Affiliated People's Hospital, Jiangsu University, Zhenjiang, Jiangsu, 212001, China.
Lin WuAffiliated Hospital of Jiangsu University, Zhenjiang, 212001, China.
Jin CaoCollege of Pharmaceutical Sciences, Jiangsu University, Zhenjiang, Jiangsu, 212013, China.
Song ShenCollege of Pharmaceutical Sciences, Jiangsu University, Zhenjiang, Jiangsu, 212013, China.
Jiangsu University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by the infiltration of inflammatory cells and proliferation of synovial cells. It can cause cartilage and bone damage as well as disability and is regarded as an incurable chronic disease. Available therapies cannot prevent the development of diseases due to the high toxicity of the therapeutic agents and the inefficient drug delivery. Ferroptosis, an iron-dependent manner of lipid peroxidative cell death, indicates great potential for RA therapy due to ability to damage the infiltrated inflammatory cells and proliferated fibroblast-like synoviocytes. Here, we use macrophages as vector to deliver Fe

Indexed as

Drug deliveryFerroptosisIron oxide nanoparticlesMacrophagesPhotothermal therapyRheumatoid arthritis

Identifiers

PMID38226012
PMCPMC10788618
OpenAlexW4389991391

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.