Evidence map›Paper›PMID 38225744›Full record

ReviewAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2024

Microneedle Sensors for Point-of-Care Diagnostics.

Yubing Hu, Eleni Chatzilakou, Zhisheng Pan, Giovanni Traverso, Ali K Yetisen

Open access · goldAbstract readReview
In one paragraph

Review in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
20.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 97 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Bioelectronic Considerations in Biomedical Microneedles.Small (Weinheim an der Bergstrasse, Germany) · 2026
    Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. SERS-Based Nano- and Microsystems Toward Biomedical Applications.Small (Weinheim an der Bergstrasse, Germany) · 2026
    Review
  11. Review
  12. Naked-Eye Visual Warning of ppmAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  13. Ionic-Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  14. Review
  15. Review
  16. Microneedle-Assisted Cell Delivery and Therapy.Research (Washington, D.C.) · 2026
    Review
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Yubing HuDepartment of Chemical Engineering, Imperial College London, London, SW7 2AZ, UK.ORCID 0000-0003-3083-0067
Eleni ChatzilakouDepartment of Chemical Engineering, Imperial College London, London, SW7 2AZ, UK.
Zhisheng PanDepartment of Chemical Engineering, Imperial College London, London, SW7 2AZ, UK.
Giovanni TraversoDepartment of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
Ali K YetisenDepartment of Chemical Engineering, Imperial College London, London, SW7 2AZ, UK.
Imperial College London · GBMassachusetts Institute of Technology · US

Funding

MISTI Global Seed Funds
6 · The paper itself

Abstract

Point-of-care (POC) has the capacity to support low-cost, accurate and real-time actionable diagnostic data. Microneedle sensors have received considerable attention as an emerging technique to evolve blood-based diagnostics owing to their direct and painless access to a rich source of biomarkers from interstitial fluid. This review systematically summarizes the recent innovations in microneedle sensors with a particular focus on their utility in POC diagnostics and personalized medicine. The integration of various sensing techniques, mostly electrochemical and optical sensing, has been established in diverse architectures of "lab-on-a-microneedle" platforms. Microneedle sensors with tailored geometries, mechanical flexibility, and biocompatibility are constructed with a variety of materials and fabrication methods. Microneedles categorized into four types: metals, inorganics, polymers, and hydrogels, have been elaborated with state-of-the-art bioengineering strategies for minimally invasive, continuous, and multiplexed sensing. Microneedle sensors have been employed to detect a wide range of biomarkers from electrolytes, metabolites, polysaccharides, nucleic acids, proteins to drugs. Insightful perspectives are outlined from biofluid, microneedles, biosensors, POC devices, and theragnostic instruments, which depict a bright future of the upcoming personalized and intelligent health management.

Indexed as

Biosensing TechniquesBiomarkersNeedlesPoint-of-Care TestingProteinsBiomarkersProteinsbiosensorsdiagnosismicroneedlespoint‐of‐caretransdermal monitoring

Identifiers

PMID38225744
PMCPMC10966570
OpenAlexW4390917036

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.