Evidence map›Paper›PMID 38225599›Full record

ArticleBMC public health2024

Retrospective cohort study of the association between socioeconomic deprivation and incidence of gestational diabetes and perinatal outcomes.

Srirangan Jeyaparam, Rochan Agha-Jaffar, Edward Mullins, Ana-Catarina Pinho-Gomes, Kamlesh Khunti, Stephen Robinson

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Article in BMC public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Srirangan JeyaparamDepartment of Metabolism, Digestion & Reproduction, Imperial College London, London, UK. sj341@student.le.ac.uk.
Rochan Agha-JaffarDepartment of Metabolism, Digestion & Reproduction, Imperial College London, London, UK.
Edward MullinsDepartment of Obstetrics & Gynaecology, Imperial College Healthcare NHS Trust, London, UK.
Ana-Catarina Pinho-GomesUniversity College London, London, UK.
Kamlesh KhuntiUniversity of Leicester, Leicester, UK.
Stephen RobinsonDepartment of Metabolic Medicine, Imperial College Healthcare NHS Trust, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSocioeconomic disparities have been shown to correlate with perinatal mortality and the incidence of type 2 diabetes. Few studies have explored the relationship between deprivation and the incidence of gestational diabetes (GDM). We aimed to identify the relationship between deprivation and incidence of GDM, after adjusting for age, BMI, and ethnicity. We also examined for relationships between deprivation and perinatal outcomes.

methodsA retrospective cohort analysis of 23,490 pregnancies from a major National Health Service Trust in Northwest London was conducted. The 2019 English Indices of Multiple Deprivation was used to identify the deprivation rank and decile for each postcode. Birthweight centile was calculated from absolute birthweight after adjusting for ethnicity, maternal height, maternal weight, parity, sex and outcome (live birth/stillbirth). Logistic regression and Kendall's Tau were used to identify relationships between variables.

resultsAfter controlling for age, BMI & ethnicity, Index of Multiple Deprivation postcode decile was not associated with an increased risk of developing gestational diabetes. Each increase in decile of deprivation was associated with an increase in birthweight centile by 0.471 (p < 0.001). After adjusting for confounders, age was associated with a 7.1% increased GDM risk (OR: 1.076, p < 0.001); BMI increased risk by 5.81% (OR: 1.059, p < 0.001). There was no significant correlation between Index of Multiple Deprivation rank and perinatal outcomes. DISCUSSION: Our analysis demonstrates that socioeconomic deprivation was not associated with incidence of GDM or adverse perinatal outcomes. Factors such as genetic predisposition and lifestyle habits may likely play a larger role in the development of GDM compared to socioeconomic deprivation alone.

Indexed as

Diabetes, GestationalDiabetes Mellitus, Type 2Birth WeightCohort StudiesFemaleHumansIncidencePregnancyPregnancy OutcomeRetrospective StudiesSocioeconomic FactorsState MedicineBirthweight centileDeprivationGestational diabetes mellitusPerinatal outcomes

Identifiers

PMID38225599
PMCPMC10790393

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.