Evidence map›Paper›PMID 38225456›Full record

ArticleLangenbeck's archives of surgery2024

The association between surgical site infection and postoperative colorectal cancer recurrence and the effect of laparoscopic surgery on prognosis.

Takuya Koike, Masaya Mukai, Kyoko Kishima, Daiki Yokoyama, Shuji Uda, Sayuri Hasegawa, Takayuki Tajima, Hideki Izumi, Eiji Nomura, Tomoko Sugiyama and 1 more

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In one paragraph

Article in Langenbeck's archives of surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 2 pooled it
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 syntheses or guidelines pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Takuya KoikeDepartment of Surgery, Tokai University Hachioji Hospital, Hachioji, Tokyo, Japan. takuyakoike118@yahoo.co.jp.ORCID http://orcid.org/0009-0007-5194-6209
Masaya MukaiDepartment of Surgery, Tokai University Hachioji Hospital, Hachioji, Tokyo, Japan.
Kyoko KishimaDepartment of Surgery, Tokai University Hachioji Hospital, Hachioji, Tokyo, Japan.
Daiki YokoyamaDepartment of Surgery, Tokai University Hachioji Hospital, Hachioji, Tokyo, Japan.
Shuji UdaDepartment of Surgery, Tokai University Hachioji Hospital, Hachioji, Tokyo, Japan.
Sayuri HasegawaDepartment of Surgery, Tokai University Hachioji Hospital, Hachioji, Tokyo, Japan.
Takayuki TajimaDepartment of Surgery, Tokai University Tokyo Hospital, Shibuya-Ku, Tokyo, Japan.
Hideki IzumiDepartment of Surgery, Tokai University Hachioji Hospital, Hachioji, Tokyo, Japan.
Eiji NomuraDepartment of Surgery, Tokai University Hachioji Hospital, Hachioji, Tokyo, Japan.
Tomoko SugiyamaDepartment of Pathology, Tokai University Hachioji Hospital, Hachioji, Tokyo, Japan.
Takuma TajiriDepartment of Pathology, Tokai University Hachioji Hospital, Hachioji, Tokyo, Japan.
Tokai University Hachioji Hospital · JPTokai University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeStudies have shown that surgical site infection (SSI) incidence is lower in patients undergoing laparoscopic surgery. Therefore, we reported the SSI countermeasures adopted by our institution and aimed to evaluate the association between SSI occurrence and postoperative colorectal cancer recurrence and the usefulness of laparoscopic surgery for prognosis.

methodsAmong the patients with colorectal cancer who underwent radical surgery at our hospital between January 2015 and December 2017, 197 with stage I-III cancer without distant metastases were included. We retrospectively analyzed patients' electronic medical records and classified them into the non-SSI (without SSI, n = 159) and SSI (with SSI, n = 38) groups. We calculated and compared the 5-year relapse-free survival (RFS) and overall survival (OS) rates. Additionally, we assessed the relationship between prognosis in the non-SSI, incisional SSI, and organ/space SSI groups and the usefulness of laparoscopic surgery.

resultsThe 5-year RFS and OS were 80.5% versus 63.2% (P = 0.024; hazard ratio [HR], 2.065; 95% confidence interval [CI], 1.099-3.883) and 88.7% versus 84.2% (P = 0.443; HR, 1.436; 95% CI, 0.570-3.617), respectively. The SSI group had a significantly worse 5-year RFS prognosis. Regarding the relationship with laparoscopic surgery, the SSI incidence was 45.0% (9/20 cases) and 16.4% (29/177 cases) with laparotomy and laparoscopic surgery, respectively, indicating a significantly reduced SSI occurrence with laparoscopic surgery (P = 0.005).

conclusionPatients with SSI were at high risk for colorectal cancer recurrence, and laparoscopic surgery may be useful for reducing SSI.

Indexed as

Colorectal NeoplasmsLaparoscopyHumansPrognosisRetrospective StudiesRisk FactorsSurgical Wound InfectionColorectal cancerLaparoscopyOpen surgeryPrognosisSurgical site infection

Identifiers

PMID38225456
OpenAlexW4390871189

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.