Evidence map›Paper›PMID 38225423›Full record

ArticleNPJ digital medicine2024

Wireless facial biosensing system for monitoring facial palsy with flexible microneedle electrode arrays.

Wenjianlong Zhou, Zhongyan Wang, Qin Xu, Xiangxiang Liu, Junshi Li, Huaiqiang Yu, Hui Qiao, Lirui Yang, Liangpeng Chen, Yuan Zhang and 13 more

Abstract read
In one paragraph

Article in NPJ digital medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Bioelectronic Considerations in Biomedical Microneedles.Small (Weinheim an der Bergstrasse, Germany) · 2026
    Review
  3. Review
  4. Article
  5. Article
  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Wenjianlong Zhou *Department of Neurosurgery, Beijing Tiantan Hospital, National Center for Neurological Disorders, Capital Medical University, 100070, Beijing, China.
Zhongyan Wang *School of Integrated Circuits, Peking University, 100871, Beijing, China.
Qin XuDepartment of Neurosurgery, Beijing Tiantan Hospital, National Center for Neurological Disorders, Capital Medical University, 100070, Beijing, China.
Xiangxiang LiuBeijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, 100730, Beijing, China.
Junshi LiSchool of Integrated Circuits, Peking University, 100871, Beijing, China.
Huaiqiang YuSichuan Institute of Piezoelectric and Acousto-optic Technology, 400060, Chongqing, China.
Hui QiaoDepartment of Neurophysiology, Beijing Neurosurgical Institute, Capital Medical University, 100070, Beijing, China.
Lirui YangDepartment of Neurophysiology, Beijing Neurosurgical Institute, Capital Medical University, 100070, Beijing, China.
Liangpeng ChenDepartment of Neurosurgery, Beijing Tiantan Hospital, National Center for Neurological Disorders, Capital Medical University, 100070, Beijing, China.
Yuan ZhangDepartment of Neurosurgery, Beijing Tiantan Hospital, National Center for Neurological Disorders, Capital Medical University, 100070, Beijing, China.
Zhe HuangSchool of Integrated Circuits, Peking University, 100871, Beijing, China.
Yuxing PangSchool of Integrated Circuits, Peking University, 100871, Beijing, China.
Zhitong ZhangSchool of Integrated Circuits, Peking University, 100871, Beijing, China.
Jiayan ZhangSchool of Integrated Circuits, Peking University, 100871, Beijing, China.
Xiudong GuanDepartment of Neurosurgery, Beijing Tiantan Hospital, National Center for Neurological Disorders, Capital Medical University, 100070, Beijing, China.
Shunchang MaDepartment of Neurosurgery, Beijing Tiantan Hospital, National Center for Neurological Disorders, Capital Medical University, 100070, Beijing, China.
Yingjie RenSchool of Integrated Circuits, Peking University, 100871, Beijing, China.
Xiaoyi ShiSchool of Integrated Circuits, Peking University, 100871, Beijing, China.
Linhao YuanDepartment of Neurosurgery, Beijing Tiantan Hospital, National Center for Neurological Disorders, Capital Medical University, 100070, Beijing, China.
Deling LiDepartment of Neurosurgery, Beijing Tiantan Hospital, National Center for Neurological Disorders, Capital Medical University, 100070, Beijing, China.ORCID http://orcid.org/0000-0002-4300-7136
Dong HuangSchool of Integrated Circuits, Peking University, 100871, Beijing, China. superhd@pku.edu.cn.
Zhihong LiSchool of Integrated Circuits, Peking University, 100871, Beijing, China. zhhli@pku.edu.cn.
Wang JiaDepartment of Neurosurgery, Beijing Tiantan Hospital, National Center for Neurological Disorders, Capital Medical University, 100070, Beijing, China. jwttyy@126.com.ORCID http://orcid.org/0000-0002-0992-6702

Funding

Beijing Postdoctoral Research Foundation 2022-ZZ-011National Natural Science Foundation of China (National Science Foundation of China) 62004007National Natural Science Foundation of China (National Science Foundation of China) 82071996
6 · The paper itself

Abstract

Facial palsy (FP) profoundly influences interpersonal communication and emotional expression, necessitating precise diagnostic and monitoring tools for optimal care. However, current electromyography (EMG) systems are limited by their bulky nature, complex setups, and dependence on skilled technicians. Here we report an innovative biosensing approach that utilizes a PEDOT:PSS-modified flexible microneedle electrode array (P-FMNEA) to overcome the limitations of existing EMG devices. Supple system-level mechanics ensure excellent conformality to the facial curvilinear regions, enabling the detection of targeted muscular ensemble movements for facial paralysis assessment. Moreover, our apparatus adeptly captures each electrical impulse in response to real-time direct nerve stimulation during neurosurgical procedures. The wireless conveyance of EMG signals to medical facilities via a server augments access to patient follow-up evaluation data, fostering prompt treatment suggestions and enabling the access of multiple facial EMG datasets during typical 6-month follow-ups. Furthermore, the device's soft mechanics alleviate issues of spatial intricacy, diminish pain, and minimize soft tissue hematomas associated with traditional needle electrode positioning. This groundbreaking biosensing strategy has the potential to transform FP management by providing an efficient, user-friendly, and less invasive alternative to the prevailing EMG devices. This pioneering technology enables more informed decision-making in FP-management and therapeutic intervention.

Identifiers

PMID38225423
PMCPMC10789865

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.