Evidence map›Paper›PMID 38225347›Full record

ArticleScientific reports2024

Understanding the exposure risk of aerosolized Coccidioides in a Valley fever endemic metropolis.

W Tanner Porter, Lalitha Gade, Parker Montfort, Joseph R Mihaljevic, Jolene R Bowers, Andrew Willman, Brian A Klimowski, Bonnie J LaFleur, Rebecca H Sunenshine, Jennifer Collins and 8 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Urban soils along the Kern River and Los Gatos Creek are hotspots forbioRxiv : the preprint server for biology · 2026
    Article
  6. Article
  7. Detection of AirborneEnvironmental science & technology letters · 2025
    Article
  8. Detection of airbornebioRxiv : the preprint server for biology · 2025
    Article
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 8 institutions in 1 country.

W Tanner Porter *Pathogen & Microbiome Division, Translational Genomics Research Institute, Flagstaff, AZ, USA. tporter@tgen.org.
Lalitha Gade *Mycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Parker MontfortPathogen & Microbiome Division, Translational Genomics Research Institute, Flagstaff, AZ, USA.
Joseph R MihaljevicSchool of Informatics, Computing, and Cyber Systems, Northern Arizona University, Flagstaff, AZ, USA.
Jolene R BowersPathogen & Microbiome Division, Translational Genomics Research Institute, Flagstaff, AZ, USA.
Andrew WillmanDepartment of Homeland Security, Phoenix, AZ, USA.
Brian A KlimowskiNational Weather Service, Flagstaff, AZ, USA.
Bonnie J LaFleurCollege of Pharmacy, The University of Arizona, Phoenix, AZ, USA.
Rebecca H SunenshineMaricopa County Department of Public Health, Phoenix, AZ, USA.
Jennifer CollinsMaricopa County Department of Public Health, Phoenix, AZ, USA.
Guillermo AdameArizona Department of Health Services, Phoenix, AZ, USA.
Shane BradyArizona Department of Health Services, Phoenix, AZ, USA.
Kenneth K KomatsuArizona Department of Health Services, Phoenix, AZ, USA.
Samantha WilliamsMycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Mitsuru TodaMycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Tom ChillerMycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Anastasia P LitvintsevaMycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, GA, USA.
David M EngelthalerPathogen & Microbiome Division, Translational Genomics Research Institute, Flagstaff, AZ, USA.
Centers for Disease Control and Prevention · USTranslational Genomics Research Institute · USArizona Department of Health Services · USMaricopa County Department of Public Health · USNOAA National Weather Service · USNorthern Arizona University · USUnited States Department of Homeland Security · USUniversity of Arizona · US

Funding

Understanding the natural Coccidioides bioaerosol in time and space and its relationship to diseaseR21AI149660 · NIAID · TRANSLATIONAL GENOMICS RESEARCH INST · PI ENGELTHALER, DAVID M · 2020 to 2021
$527k
NIAID NIH HHS R21 AI149660NIH HHS 5R21AI149660-02
6 · The paper itself

Abstract

Coccidioides is the fungal causative agent of Valley fever, a primarily pulmonary disease caused by inhalation of fungal arthroconidia, or spores. Although Coccidioides has been an established pathogen for 120 years and is responsible for hundreds of thousands of infections per year, little is known about when and where infectious Coccidioides arthroconidia are present within the ambient air in endemic regions. Long-term air sampling programs provide a means to investigate these characteristics across space and time. Here we present data from > 18 months of collections from 11 air sampling sites across the Phoenix, Arizona, metropolitan area. Overall, prevalence was highly variable across space and time with no obvious spatial or temporal correlations. Several high prevalence periods were identified at select sites, with no obvious spatial or temporal associations. Comparing these data with weather and environmental factor data, wind gusts and temperature were positively associated with Coccidioides detection, while soil moisture was negatively associated with Coccidioides detection. These results provide critical insights into the frequency and distribution of airborne arthroconidia and the associated risk of inhalation and potential disease that is present across space and time in a highly endemic locale.

Indexed as

CoccidioidomycosisArizonaCoccidioidesSpores, FungalTemperatureWeather

Identifiers

PMID38225347
PMCPMC10789871
OpenAlexW4390880626

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.