Evidence map›Paper›PMID 38225272›Full record

ArticleNature communications2024

Amyloid beta 42 alters cardiac metabolism and impairs cardiac function in male mice with obesity.

Liam G Hall, Juliane K Czeczor, Timothy Connor, Javier Botella, Kirstie A De Jong, Mark C Renton, Amanda J Genders, Kylie Venardos, Sheree D Martin, Simon T Bond and 8 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Amyloid-beta (1-40) peptide is associated with systemic metabolic health.European journal of clinical investigation · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Experimental laboratory models as tools for understanding modifiable dementia risk.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 3 institutions in 3 countries.

Liam G Hall *Institute for Mental and Physical Health and Clinical Translation, Metabolic Research Unit, School of Medicine, Deakin University, Geelong, Australia.ORCID 0000-0001-5504-0374
Juliane K Czeczor *Institute for Mental and Physical Health and Clinical Translation, Metabolic Research Unit, School of Medicine, Deakin University, Geelong, Australia.
Timothy ConnorInstitute for Mental and Physical Health and Clinical Translation, Metabolic Research Unit, School of Medicine, Deakin University, Geelong, Australia.
Javier BotellaInstitute for Mental and Physical Health and Clinical Translation, Metabolic Research Unit, School of Medicine, Deakin University, Geelong, Australia.ORCID 0000-0001-9722-8519
Kirstie A De JongInstitute for Mental and Physical Health and Clinical Translation, Metabolic Research Unit, School of Medicine, Deakin University, Geelong, Australia.
Mark C RentonInstitute for Physical Activity and Nutrition, School of Exercise and Nutrition Sciences, Deakin University, Geelong, Australia.ORCID 0000-0003-0909-7948
Amanda J GendersInstitute for Mental and Physical Health and Clinical Translation, Metabolic Research Unit, School of Medicine, Deakin University, Geelong, Australia.
Kylie VenardosInstitute for Mental and Physical Health and Clinical Translation, Metabolic Research Unit, School of Medicine, Deakin University, Geelong, Australia.
Sheree D MartinInstitute for Mental and Physical Health and Clinical Translation, Metabolic Research Unit, School of Medicine, Deakin University, Geelong, Australia.
Simon T BondInstitute for Mental and Physical Health and Clinical Translation, Metabolic Research Unit, School of Medicine, Deakin University, Geelong, Australia.ORCID 0000-0003-1551-8614
Kathryn Aston-MourneyInstitute for Mental and Physical Health and Clinical Translation, Metabolic Research Unit, School of Medicine, Deakin University, Geelong, Australia.
Kirsten F HowlettInstitute for Physical Activity and Nutrition, School of Exercise and Nutrition Sciences, Deakin University, Geelong, Australia.ORCID 0000-0002-8571-4867
James A CampbellAmbetex Pty Ltd, Geelong, Australia.ORCID 0000-0003-3183-5417
Greg R CollierAmbetex Pty Ltd, Geelong, Australia.
Ken R WalderInstitute for Mental and Physical Health and Clinical Translation, Metabolic Research Unit, School of Medicine, Deakin University, Geelong, Australia.
Matthew McKenzieSchool of Life and Environmental Science, Deakin University, Geelong, Australia.
Mark ZiemannSchool of Life and Environmental Science, Deakin University, Geelong, Australia.
Sean L McGeeInstitute for Mental and Physical Health and Clinical Translation, Metabolic Research Unit, School of Medicine, Deakin University, Geelong, Australia. sean.mcgee@deakin.edu.au.ORCID 0000-0001-6953-106X
Deakin University · AUBaker Heart and Diabetes Institute · AUUniversity of British Columbia · CA

Funding

Department of Health | National Health and Medical Research Council (NHMRC) GNT1027226Diabetes Australia Research Trust (DART) Y17G-MCGS
6 · The paper itself

Abstract

There are epidemiological associations between obesity and type 2 diabetes, cardiovascular disease and Alzheimer's disease. The role of amyloid beta 42 (Aβ

Indexed as

Alzheimer DiseaseDiabetes Mellitus, Type 2Amyloid beta-PeptidesAnimalsAntibodies, NeutralizingGlucoseMaleMiceObesityPeptide FragmentsAmyloid beta-PeptidesAntibodies, NeutralizingGlucosePeptide Fragments

Identifiers

PMID38225272
PMCPMC10789867
OpenAlexW4390885656

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.